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Serine-Threonine Kinase 3

An intracellular-signaling kinase that plays a role in regulating APOPTOSIS.

Also Known As:

Serine Threonine Kinase 3; STK3 Protein Serine Threonine Kinase

Networked: 37 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Zhang, Yan: 2 articles (12/2020 - 10/2020)
2.	Kepp, Oliver: 2 articles (01/2017 - 06/2016)
3.	Kroemer, Guido: 2 articles (01/2017 - 06/2016)
4.	Chung, Kyung Soo: 1 article (04/2022)
5.	Kim, Junhyung: 1 article (04/2022)
6.	Kim, Young Sam: 1 article (04/2022)
7.	Lee, Jin Hwa: 1 article (04/2022)
8.	Lee, Su Hwan: 1 article (04/2022)
9.	Moon, Jong-Seok: 1 article (04/2022)
10.	Na, Sungwon: 1 article (04/2022)

Related Diseases

1.	Necrosis 01/20/2012 - "The receptor-interacting serine-threonine kinase 3 (RIP3) is a key signaling molecule in the programmed necrosis (necroptosis) pathway. " 01/01/2016 - "A second pathway mediating necrosis involves Receptor-Interacting Serine-Threonine Kinase 3 (RIPK3); in this study we sought to investigate the impact of RIPK3 on the development of lupus and nephritis in both sexes. " 10/01/2020 - "Necroptosis is a regulated cell death that is governed by mixed lineage kinase domain-like, receptor-interacting serine-threonine kinase 3 and commonly displays with necrosis morphological characteristics. " 11/01/2018 - "Necroptosis is an inflammatory form of cell death that depends on receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and displays the morphological characteristics of necrosis. " 01/24/2017 - "Necroptosis is a form of regulated cell death that critically depends on receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and generally manifests with morphological features of necrosis. "
2.	Thymoma (Thymic Carcinoma) 12/01/2021 - "Quantitative real-time polymerase chain reaction (qRT-PCR) was implemented to measure the expression of circ_0016760, microRNA-646 (miR-646) and AK strain thymoma serine/threonine kinase 3 (AKT3). " 12/01/2016 - "In total, 98 patients were included in this retrospective translational research study and were evaluated for Kirsten rat sarcoma viral oncogene homolog (KRAS) mutational status, and v-akt murine thymoma viral oncogene homolog 1 (AKT1), AKT serine/threonine kinase 2 (AKT2), AKT serine/threonine kinase 3 (AKT3), cyclin D1 (CCND1), epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), hepatocellular growth factor receptor (MET), avian myelomatosis viral oncogene homolog (MYC), nuclear factor kappa B subunit 1 (NFKb1), phosphatase and tensin homolog (PTEN) and mechanistic target of rapamycin (FRAP1) genes mRNA expression. "
3.	Sarcoma (Soft Tissue Sarcoma) 12/01/2016 - "In total, 98 patients were included in this retrospective translational research study and were evaluated for Kirsten rat sarcoma viral oncogene homolog (KRAS) mutational status, and v-akt murine thymoma viral oncogene homolog 1 (AKT1), AKT serine/threonine kinase 2 (AKT2), AKT serine/threonine kinase 3 (AKT3), cyclin D1 (CCND1), epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), hepatocellular growth factor receptor (MET), avian myelomatosis viral oncogene homolog (MYC), nuclear factor kappa B subunit 1 (NFKb1), phosphatase and tensin homolog (PTEN) and mechanistic target of rapamycin (FRAP1) genes mRNA expression. "
4.	Nephritis 01/01/2016 - "A second pathway mediating necrosis involves Receptor-Interacting Serine-Threonine Kinase 3 (RIPK3); in this study we sought to investigate the impact of RIPK3 on the development of lupus and nephritis in both sexes. "
5.	Multiple Myeloma 12/01/2016 - "In total, 98 patients were included in this retrospective translational research study and were evaluated for Kirsten rat sarcoma viral oncogene homolog (KRAS) mutational status, and v-akt murine thymoma viral oncogene homolog 1 (AKT1), AKT serine/threonine kinase 2 (AKT2), AKT serine/threonine kinase 3 (AKT3), cyclin D1 (CCND1), epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), hepatocellular growth factor receptor (MET), avian myelomatosis viral oncogene homolog (MYC), nuclear factor kappa B subunit 1 (NFKb1), phosphatase and tensin homolog (PTEN) and mechanistic target of rapamycin (FRAP1) genes mRNA expression. "

Related Drugs and Biologics

1.	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)
2.	Sirolimus (Rapamycin)
3.	Messenger RNA (mRNA)
4.	Phosphoric Monoester Hydrolases (Phosphatases)
5.	ErbB Receptors (EGF Receptor)
6.	Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)
7.	Cyclin D1
8.	Growth Factor Receptors
9.	NF-kappa B (NF-kB)
10.	Tensins

Related Therapies and Procedures

1.	Therapeutics