Anticoagulant Reversal Agents

Agents that have the potential to reverse specific anticoagulation therapies.

Also Known As:

Agents, Anticoagulant Reversal; Agents, Anticoagulation Reversal; Agents, Antithrombotic Reversal; Drugs, Anticoagulant Reversal; Reversal Agents, Anticoagulant; Reversal Agents, Anticoagulation; Reversal Agents, Antithrombotic; Reversal Drugs, Anticoagulant; Anticoagulant Reversal Drugs; Anticoagulation Reversal Agents; Antithrombotic Reversal Agents

Networked: 8 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Therapeutic Uses: 47080
    - Hematologic Agents: 2
      - Coagulants: 1747
        Hemostatics: 9671
        Anticoagulant Reversal Agents: 8

Experts

1.	Levy, Jerrold H: 2 articles (11/2016 - 11/2016)
2.	Milling, Truman J: 1 article (11/2021)
3.	Refaai, Majed A: 1 article (11/2021)
4.	Sengupta, Neil: 1 article (11/2021)
5.	Brinkley, Marshall: 1 article (09/2019)
6.	Brown Sacks, Suzanne: 1 article (09/2019)
7.	Danter, Matthew: 1 article (09/2019)
8.	Hanna, Peter: 1 article (09/2019)
9.	Keebler, Mary: 1 article (09/2019)
10.	Lindenfeld, Joann: 1 article (09/2019)

Related Diseases

1.	Hematoma 12/01/2015 - "Recent advances such as newer laboratory testing and rapid computed tomography for diagnosis, blood pressure reduction to reduce hematoma expansion, and new anticoagulant reversal agents may allow for improved outcomes. "
2.	Stroke (Strokes) 05/01/2022 - "The aim of this study was to determine the impact of a dedicated stroke response team on timeliness of blood pressure control, administration of anticoagulation reversal agents, and emergency department arrival to a critical care bed. "
3.	Hemorrhage 11/01/2021 - "The utility of anticoagulant reversal agents in GI bleeding is recognized in guidelines; however, such agents should be reserved for use in truly life-threatening scenarios." 11/01/2016 - "As clinical development of the additional anti-FXa-specific anticoagulant reversal agents proceeds, the respective role of each in the management of emergency bleeding events and invasive procedures will be better defined, and it is hoped they will make important contributions to patient care." 11/01/2016 - "As clinical development of the additional anti-FXa-specific anticoagulant reversal agents proceeds, the respective role of each in the management of emergency bleeding events and invasive procedures will be better defined, and it is hoped they will make important contributions to patient care." 09/01/2019 - "Anticoagulation reversal agents (ARAs) can minimize bleeding complications associated with mechanical circulatory support devices (MCSDs) explantation at the time of heart transplantation (HT); data on thromboembolic (TE) risk associated with ARAs are limited in this patient population. " 11/01/2021 - "To review current US, as well as international, guidelines for anticoagulant reversal agents in patients on VKAs or DOACs presenting with GI bleeding prior to endoscopy, guideline-based management of coagulation defects, timing of endoscopy, and recommendations for resumption of anticoagulant therapy following hemostasis. "
4.	Intracranial Hemorrhages (Intracranial Hemorrhage) 11/01/2022 - "Evaluation of Direct Oral Anticoagulant Reversal Agents in Intracranial Hemorrhage: A Systematic Review and Meta-analysis." 01/01/2019 - "Coagulopathy reversal agents, antithrombotic regimens, and thrombotic (venous thromboembolism, ischemic stroke, myocardial infarction) and hemorrhagic (recurrent intracranial hemorrhage, gastrointestinal bleed, anemia requiring transfusion) complications were recorded. "
5.	Venous Thromboembolism 01/01/2019 - "Coagulopathy reversal agents, antithrombotic regimens, and thrombotic (venous thromboembolism, ischemic stroke, myocardial infarction) and hemorrhagic (recurrent intracranial hemorrhage, gastrointestinal bleed, anemia requiring transfusion) complications were recorded. "

Related Drugs and Biologics

1.	Anticoagulants

Related Therapies and Procedures

1.	Critical Care (Surgical Intensive Care)
2.	Heart Transplantation (Grafting, Heart)
3.	Therapeutics