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Type B Trichothecenes

A subclass of Trichothecene derivatives that include the 12,13-epoxytrichothec-9-ene structure with a keto (carbonyl) function at C-8.

Also Known As:

Trichothecenes, Type B

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Trichothecenes: 97
        Type B Trichothecenes: 4
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Trichothecenes: 97
    - Type B Trichothecenes: 4
Biological Factors: 2472
- Biological Toxins: 20
  - Mycotoxins: 1745
    - Trichothecenes: 97
      - Type B Trichothecenes: 4

Experts

1.	Wu, Wenda: 2 articles (01/2018 - 04/2016)
2.	Liu, Shengli: 1 article (01/2018)
3.	Zhang, Haibin: 1 article (01/2018)
4.	Zhang, Hua: 1 article (01/2018)
5.	Zhang, Jie: 1 article (01/2018)
6.	Bursian, Steven J: 1 article (04/2016)
7.	Link, Jane E: 1 article (04/2016)
8.	Pestka, James J: 1 article (04/2016)
9.	Zhou, Hui-Ren: 1 article (04/2016)
10.	Bosch, Remko R: 1 article (09/2006)

Related Diseases

1.	Anorexia 12/18/2022 - "To summarize, the results suggest that both SP and GLP-1 play important roles in anorexia induction by type B trichothecenes." 01/01/2018 - "Although anorexia is a common hallmark of type B trichothecenes-induced toxicity, less is known about the anorectic potencies of type A trichothecenes. "
2.	Vomiting 04/01/2016 - "Deoxynivalenol (DON, vomitoxin) and other Type B trichothecenes have been previously demonstrated to cause emesis in the mink (Neovison vison), and this response has been directly linked to secretion of both the satiety hormone peptide YY3-36 (PYY3-36) and neurotransmitter 5-hydroxytryptamine (5-HT). "
3.	Necrosis 09/01/2006 - "In contrast, type A trichothecenes reduce the mitochondrial activity at approximately 1000-fold lower concentrations than the type B trichothecenes, resulting in necrosis. "

Related Drugs and Biologics

1.	Type A Trichothecenes
2.	Glucagon-Like Peptide 1 (GLP 1)
3.	Peptide Hormones (Polypeptide Hormones)
4.	Neurotransmitter Agents (Neurotransmitter)
5.	Serotonin (5 Hydroxytryptamine)
6.	Appetite Depressants (Anorectics)
7.	deoxynivalenol