Etoricoxib

A sulfone and pyridine derivative that acts as a cyclooxygenase-2 inhibitor. It is used as a NSAID for the treatment of pain associated with RHEUMATOID ARTHRITIS and ANKYLOSING SPONDYLITIS. It is also used for the short-term treatment of moderate postoperative dental pain.

Also Known As:

Networked: 452 relevant articles (103 outcomes, 158 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Curtis, Sean P: 19 articles (10/2013 - 05/2002)
2.	Peloso, Paul M: 13 articles (10/2016 - 12/2010)
3.	Smugar, Steven S: 11 articles (12/2012 - 07/2007)
4.	Mehta, Anish: 9 articles (10/2016 - 01/2011)
5.	Gammaitoni, Arnold: 9 articles (02/2015 - 12/2010)
6.	Wang, Hongwei: 9 articles (02/2015 - 04/2009)
7.	Cannon, Christopher P: 9 articles (12/2012 - 08/2006)
8.	Laine, Loren: 9 articles (12/2012 - 08/2006)
9.	Moore, R Andrew: 8 articles (10/2016 - 01/2008)
10.	Sanyal, Sankar Nath: 8 articles (01/2016 - 01/2008)

Related Diseases

1.	Pain (Aches) 02/20/2018 - "Pain relief, joint function, quality of life, and treatment satisfaction improved significantly in elderly patients with OA after etoricoxib administration." 01/01/2016 - "The Brief Pain Inventory (pain scores), PD-Q, WOMAC, and walking and stair climbing tests were all significantly improved by etoricoxib. " 04/01/2015 - "We found that perioperative use of etoricoxib produced a significant reduction in the degree of pain compared to the patients treated with placebo. " 08/01/2003 - "Etoricoxib provided significant improvement from baseline versus placebo in pain intensity (4 weeks: 12.9 mm and 10.3 mm for 60-mg and 90-mg doses, P <.001 for each; 12 weeks: 10.5 mm and 7.5 mm for 60-mg and 90-mg doses, P =.001 and.018, respectively). " 05/01/2019 - "Group I patients showed better improvement in terms of functional impairment (Inability Walking Scale), reported pain (visual analogue scale), and daily intake of etoricoxib 60 mg. Athletes of group I registered a faster resuming of sport activities. "
2.	Osteoarthritis 01/01/2008 - "Information was sought from a dose-response trial over 6 weeks in osteoarthritis using placebo and using etoricoxib at 5, 10, 30 and 60 mg daily. " 12/01/2005 - "The aim of this study was to evaluate the long-term efficacy and tolerability of etoricoxib, a COX-2 selective inhibitor, in osteoarthritis (OA) patients. " 12/01/2005 - "Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489]." 09/01/2002 - "To evaluate the clinical efficacy and tolerability of etoricoxib in the treatment of osteoarthritis (OA) of the knee and define the clinically active dose range for further clinical trials. " 09/01/2002 - "Results of a randomized, dose-ranging trial of etoricoxib in patients with osteoarthritis."
3.	Rheumatoid Arthritis 01/01/2002 - "In patients with rheumatoid arthritis, improvements in tender and swollen joint counts and patient and investigator global assessment of disease activity were significantly greater in etoricoxib than in placebo recipients in two studies. " 10/01/2011 - "Further assessment of the clinically effective dose range of etoricoxib: a randomized, double-blinded, placebo-controlled trial in rheumatoid arthritis." 10/01/2011 - "To further assess the clinically active dose range of etoricoxib, a COX-2 selective inhibitor, in rheumatoid arthritis (RA). " 08/01/2002 - "A randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis." 05/22/2002 - "A multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273]."
4.	Postoperative Pain 05/08/2014 - "Randomised, double-blind, placebo-controlled clinical trials of single dose, oral etoricoxib for acute postoperative pain in adults. " 12/01/2012 - "Evaluation of a single preoperative dose of etoricoxib for postoperative pain relief in therapeutic knee arthroscopy: a randomized trial." 04/18/2012 - "Randomised, double-blind, placebo-controlled clinical trials of single dose, oral etoricoxib for acute postoperative pain in adults. " 04/15/2009 - "Randomised, double-blind, placebo-controlled clinical trials of single dose, oral etoricoxib for acute postoperative pain in adults. " 01/01/2021 - "Scores for the post-operative pain in the etoricoxib group were significantly lower than those in the placebo group during first 12 h (p < 0.05). "
5.	Ankylosing Spondylitis 04/01/2005 - "Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty-two-week, randomized, controlled study." 04/01/2019 - "Efficacy of etoricoxib for ankylosing spondylitis: A protocol for systematic review of randomized controlled trial." 04/01/2019 - "Previous clinical trials have reported that etoricoxib has been utilized to treat ankylosing spondylitis (AS) effectively. " 05/29/2020 - "Conclusions: The nonsteroidal anti-inflammatory drugs, in our case, etoricoxib, facilitate the application of individualized exercise programs in patients with ankylosing spondylitis." 05/29/2020 - "Non-Steroidal Anti-Inflammatory Drug Etoricoxib Facilitates the Application of Individualized Exercise Programs in Patients with Ankylosing Spondylitis."

Related Drugs and Biologics

1.	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
2.	Diclofenac (SR 38)
3.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
4.	Naproxen (Naprosyn)
5.	Celecoxib (Celebrex)
6.	Analgesics (Analgesic Drugs)
7.	Ibuprofen (Motrin)
8.	Indomethacin (Indometacin)
9.	Acetaminophen (Paracetamol)
10.	rofecoxib (Vioxx)

Related Therapies and Procedures

1.	Hip Replacement Arthroplasty (Total Hip Replacement)
2.	Therapeutics
3.	Analgesia
4.	Laparoscopic Cholecystectomy
5.	Debridement