Aluminum Chloride

A compound with the chemical formula AlCl3; the anhydrous salt is used as a catalyst in organic chemical synthesis, and hydrated salts are used topically as antiperspirants, and for the management of HYPERHYDROSIS.

Also Known As:

Networked: 410 relevant articles (41 outcomes, 70 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Li, Yanfei: 14 articles (01/2022 - 10/2011)
2.	Manivasagam, Thamilarasan: 8 articles (05/2019 - 04/2015)
3.	Zhu, Yanzhu: 7 articles (01/2017 - 10/2011)
4.	Zhao, Hansong: 6 articles (01/2017 - 10/2011)
5.	Shao, Bing: 5 articles (01/2022 - 10/2011)
6.	Essa, Musthafa Mohamed: 5 articles (05/2019 - 07/2016)
7.	Justin Thenmozhi, Arokiasamy: 5 articles (07/2017 - 04/2015)
8.	Nampoothiri, Madhavan: 5 articles (06/2017 - 12/2013)
9.	Hu, Chongwei: 5 articles (08/2012 - 10/2011)
10.	Song, Miao: 4 articles (01/2022 - 01/2017)

Related Diseases

1.	Cognitive Dysfunction 03/15/2016 - "KXS significantly improved the cognitive impairment induced by d-gal and AlCl3, attenuated hippocampal histopathological abnormalities, reduced Aβ1-40 levels and increased Bcl-2 and ChAT expression in the hippocampus. " 01/01/2022 - "WERG improved the cognitive impairment of D-gal/AlCl3-induced mice. " 01/01/2021 - "For in vivo studies, we observed that Aβ accumulation, Tau hyperphosphorylation, neurons of hippocampal damage, and cognitive dysfunction in AD mice, caused by bilateral injection of Aβ1-42 into the hippocampus and treatments with D-gal combine AlCl3. " 04/01/2015 - "The present study suggests the neuro-protection by SML against cognitive dysfunction induced by environmental toxin (AlCl3) in hippocampus and frontal cortex." 11/17/2023 - "Microglia were hyperactivated in the brains of AlCl3/D-gal-treated mice, which was associated with cognitive decline. "
2.	Hyperhidrosis 12/01/2022 - "To compare the efficacy of tap water iontophoresis (TWI) versus aluminum chloride (AC) hexahydrate in the treatment of palmoplantar hyperhidrosis. " 12/01/2022 - "Comparison of the Efficacy of Tap Water Iontophoresis Versus Aluminum Chloride Hexahydrate in the Treatment of Palmoplantar Hyperhidrosis." 06/30/2023 - "Conclusion The present study provides preliminary evidence suggesting that aluminum chloride hexahydrate gel iontophoresis is an effective alternative treatment to decrease sweating rate in extended areas with fewer side effects in patients with primary palmar hyperhidrosis." 06/30/2023 - "This study investigated the effect of aluminum chloride hexahydrate gel iontophoresis compared to tap water iontophoresis on primary palmar hyperhidrosis. " 06/30/2023 - "Currently, iontophoresis with tap water and aluminum chloride hexahydrate is used for primary palmar hyperhidrosis. "
3.	Alzheimer Disease (Alzheimer's Disease) 06/11/2021 - "A Leaf Extract of Harrisonia abyssinica Ameliorates Neurobehavioral, Histological and Biochemical Changes in the Hippocampus of Rats with Aluminum Chloride-Induced Alzheimer's Disease." 01/01/2019 - "In a d‑galactose and aluminum trichloride Alzheimer's disease (AD) mouse model, 42-day administration of ACPS improved the abnormal behaviors. " 01/01/2023 - "A rat Alzheimer's disease (AD) model was established by intracerebroventricular injection of Aβ25-35 combined with AlCl3 and RHTGF-β1. " 12/22/2022 - "Characterization of Orange Peel Extract and Its Potential Protective Effect against Aluminum Chloride-Induced Alzheimer's Disease." 10/01/2022 - "Chronic oral exposure of aluminum chloride in rat modulates molecular and functional neurotoxic markers relevant to Alzheimer's disease."
4.	Memory Disorders (Memory Loss) 12/01/2023 - "The low dose of 5 mg/kg is more effective than a high dose of 10 mg/kg. In accordance with these findings, myco-fabricated ZnO-NPs could enhance memory and exhibit a protective influence against memory loss caused by AlCl3." 10/01/2023 - "Our results showed that AlCl3 induced mice memory disorder, BBB destruction, and pathological injury. " 01/01/2022 - "AlCl3 induced learning and memory deficit in zebrafish." 03/01/2006 - "To examine the protective effect of Ginkgo biloba leaf extract (GbE) on learning and memory deficit induced by aluminum chloride (AlCl(3)), and explore its mechanisms. " 05/01/2016 - "Our results suggest AlCl3 can induce neuroinflammation that may result in loss of spine, and thereby leads to learning and memory deficits. "
5.	Neuroinflammatory Diseases 05/01/2016 - "Aluminum chloride induces neuroinflammation, loss of neuronal dendritic spine and cognition impairment in developing rat." 05/01/2016 - "Our results suggest AlCl3 can induce neuroinflammation that may result in loss of spine, and thereby leads to learning and memory deficits. " 11/01/2020 - "To the contrary, co-administration of BEO and AlCl3 improved the anxiety-like behavior, GABA system, oxidative stress and neuroinflammation. " 09/04/2023 - "Neuroprotective and Cardiometabolic Role of Vitamin E: Alleviating Neuroinflammation and Metabolic Disturbance Induced by AlCl3 in Rat Models." 08/01/2023 - "Biochemical profiling of berberine-enriched extract in aluminum chloride induced oxidative damage and neuroinflammation."

Related Drugs and Biologics

1.	Galactose (Galactopyranose)
2.	Aluminum Chloride
3.	Aluminum
4.	Solutions
5.	Salicylic Acid (2 Hydroxybenzoic Acid)
6.	Ointments (Pastes)
7.	Resveratrol
8.	Epinephrine (Adrenaline)
9.	Polytetrafluoroethylene (Teflon)
10.	Antioxidants

Related Therapies and Procedures

1.	Therapeutics
2.	Curettage
3.	Critical Care (Surgical Intensive Care)
4.	Intraperitoneal Injections
5.	Lasers (Laser)