Diverticular Diseases

03/23/2023 - "Rifaximin effectively treats symptomatic uncomplicated diverticular disease (SUDD) and has shown eubiotic potential (i.e., an increase in resident microbial elements with potential beneficial effects) in other diseases. "
02/23/2023 - "Current evidence shows that cyclical rifaximin usage in conjunction with a high-fiber diet is safe and effective for treating symptomatic uncomplicated diverticular disease, while the cost-effectiveness of long-term treatment is unknown. "
06/01/2017 - "The cyclic use of rifaximin, in association with high-fibre intake, is safe and useful for the treatment of symptomatic uncomplicated diverticular disease, even if the cost-efficacy of long-term treatment remains to be determined. "
01/01/2012 - "The evidence from prospective controlled trials suggests that rifaximin is effective for obtaining symptomatic relief in patients with uncomplicated diverticular disease. "
04/01/2011 - "In symptomatic uncomplicated diverticular disease, treatment with rifaximin plus fibre supplementation is effective in obtaining symptom relief and preventing complications at 1 year."

03/01/2007 - "Daily mesalazine supplying seems to be more effective than cyclic supplying in maintaining remission in recurrent symptomatic uncomplicated diverticular disease."
08/01/2006 - "Some recent studies confirm the efficacy of mesalazine in diverticular disease both in relief of symptoms in symptomatic uncomplicated forms and in prevention of recurrence of symptoms and main complications."
02/01/2010 - "To assess the therapeutic efficacy of 5-aminosalicylic acid (5-ASA) in patients with colonic diverticular disease performing a systematic review of the literature. "
09/01/2008 - "We found mesalazine effective in reducing the colonic cell proliferation in long-term treatment for colonic diverticular disease."
11/01/2007 - "We conclude that cyclic administration of mesalazine is effective for symptomatic relief of uncomplicated diverticular disease of the colon. "

11/01/1992 - "Prospective studies with an adequate sample size per group of treatment are needed to assess the efficacy of cyclic long term administration of poorly absorbable antibiotics in preventing major complications of diverticular disease."
12/01/1994 - "Broad-spectrum antibiotics, diagnostic and therapeutic computed tomography scans, and early surgical intervention have improved the treatment of hospitalized patients with diverticular disease. "
01/01/2022 - "Treatment of diverticular disease should be individualized and include modification of lifestyle, use of antibiotics, and surgery. "
08/01/2021 - "Data from two centers with a routine use of oral antibiotic bowel decontamination for up to 20 years of experience were analyzed for the perioperative outcome of 384 patients undergoing surgery for diverticular disease. "
08/01/2021 - "Oral antibiotic bowel decontamination in open and laparoscopic sigmoid resections for diverticular disease."

01/01/2022 - "Localizing spontaneously hemostatic colonic diverticular bleeding using VISCOCLEAR gel: A case report."
08/01/2001 - "We identified 13 patients who underwent colonoscopic hemostatic management for the treatment of acute diverticular bleeding. "
06/29/2021 - "Efficacy of Over-The-Scope Clip Method as a Novel Hemostatic Therapy for Colonic Diverticular Bleeding."
09/02/2022 - "HSE-C is associated with a higher rate of successful primary hemostasis for severe active diverticular bleeding but has no significant difference in reducing early recurrent bleeding or the number of patients requiring surgery, suggesting that hemostatic effects may be temporary."
01/01/2022 - "Over-the-scope clipping and detachable snare ligation as a novel combination hemostatic therapy for diverticular bleeding."

02/01/2012 - "Lifestyle factors other than dietary fiber intake and risk for colonic diverticular disease have only been examined in few studies. "
11/01/1985 - "The relationship between consumption of dietary fiber (DF) from white bread, wholemeal bread, or bran and the development of diverticular disease of the colon has been investigated in a lifespan study using 1800 Wistar rats in nine diet groups. "
11/01/1985 - "Cereal dietary fiber consumption and diverticular disease: a lifespan study in rats."
07/01/1981 - "Clinical trials in which symptomatic diverticular disease was treated with supplementary dietary fiber have generally had favorable results. "
03/01/2023 - "In diverticular disease, the microbiome presents an intriguing potential link between the disease and its long-established risk factors, dietary fiber and industrialization. "

08/01/1990 - "Lactulose and high-fibre diet were both shown to be effective in the treatment of diverticular disease, with some differences in favour of lactulose."
03/01/2006 - "SIBO was eradicated in all pts completing the study, while a new lactulose H2-BT showed persistence of SIBO in one pt with recurrence of symptomatic diverticular disease. "
08/01/1990 - "To compare the efficacy and tolerance of lactulose (Duphalac) and high-fibre diet in the treatment of symptomatic diverticular disease. "
08/01/1990 - "Lactulose in the treatment of symptomatic diverticular disease: a comparative study with high-fibre diet."
03/01/2006 - "Ninety consecutive patients (pts; 39 males, 51 females; mean age, 67.2 years; range, 32-91 years) affected by symptomatic uncomplicated diverticular disease of the colon were evaluated to assess orocecal transit time (OCTT), SIBO, and LM by lactulose and lactose H2 breath test (H2-BT) at entry and after 8 weeks of treatment. "

01/01/2009 - "Information about faecal calprotectin (FC) in colonic diverticular disease (DD) are lacking. "
01/01/2009 - "Faecal calprotectin in colonic diverticular disease: a case-control study."
01/01/2023 - "Diverticular Inflammation and Complication Assessment classification, CODA score and fecal calprotectin in clinical assessment of patients with diverticular disease: A decision curve analysis."
03/01/2015 - "Moderate to severe and prolonged left lower-abdominal pain is the best symptom characterizing symptomatic uncomplicated diverticular disease of the colon: a comparison with fecal calprotectin in clinical setting."
08/01/2018 - "Expert commentary: A combination of clinical characteristic of the abdominal pain and fecal calprotectin expression may help to differentiate between symptomatic uncomplicated diverticular disease and irritable bowel syndrome. "

11/01/2013 - "We conducted a retrospective study of the efficacy of a polyethylene glycol purge before colonoscopic examination in 110 patients with colonic diverticular bleeding. "
01/01/2020 - "We report a case of colonic diverticular bleeding associated with a bowel cleanser (137 g of polyethylene glycol [NIflec®]) before colonoscopy (CS). "
03/01/1974 - "In colonic diverticular disease (n = 7) the rate of throughput of polyethylene glycol was significantly lower. "
01/01/2021 - "Severe Acute Colonic Diverticular Bleeding: The Efficacy of Rapid Bowel Preparation With 1 L Polyethylene Glycol Ascorbate Solution and Direct Endoscopic Hemoclipping for Successful Hemostasis."
01/01/2021 - "We hereby delineate the importance of rapid bowel preparation with a very-low-volume novel 1 L polyethylene glycol ascorbate solution in the setting of acute severe colonic diverticular bleeding. "

11/01/2015 - " aim of this systematic review is to define the best treatment for colonic diverticular bleeding.A systematic bibliographic research was performed on the online databases for studies (randomized controlled trials [RCTs], observational trials, case series, and case reports) published between 2005 and 2014, concerning patients admitted with a diagnosis of diverticular bleeding according to the PRISMA methodology.The"
03/01/2016 - "According to PRISMA, we identified studies on diverticular disease patients treated with probiotics (Pubmed, Embase, Cochrane). "

01/01/2012 - "The purpose of the research was the study of the prebiotic and hypolipidemic effects of 12-week treatment by psillium of patients with uncomplicated diverticular disease and hyperlipidemia. "
08/01/2007 - "Prebiotic and probiotic therapies are new strategies that are being used to treat different gastrointestinal diseases, such as irritable bowel syndrome, diverticular disease and inflammatory bowel diseases. "
08/31/2019 - "Efficacy of combined prophylactic therapy (rifaximine alpha + prebiotic arabinogalactan with lactofferin) on GUT function in patients with diagnosed symptomatic uncomplicated diverticular disease."
11/01/2018 - "Mannans improve the texture and appeal of food products and provide numerous health benefits like controlling obesity and body weight control, prebiotic benefits, constipation alleviaton, prevent occurrence of diarrhea, check inflammation due to gut related diseases, management of diverticular disease management, balance intestinal microbiota, immune system modulator, reduced risk of colorectal cancer etc. Mannan degrading enzymes are the key enzymes involved in degradation and are useful in various industrial processes such as fruit juice clarification, viscosity reduction of coffee extracts etc. besides facilitating the process steps and improving process quality."

02/01/2006 - "Elective laparoscopic colectomy for diverticular disease is feasible, safe and gives very good results: minimum postoperative discomfort, rapid recovery, low mobility and postoperative stay, rapid return to normal activities. "
06/01/2023 - "Consecutive patients who benefited from sigmoid colectomy for diverticular disease from January 2007 to June 2021 were identified based on operative codes. "
07/01/2000 - "There were two false-positive results of positron emission tomography: increased F18-fluorodeoxyglucose uptake in the contralateral chest that was negative by thoracoscopic biopsy (n = 1) and increased abdominal F18-fluorodeoxyglucose uptake after partial colectomy for diverticular disease (n = 1). "
03/01/2015 - "Proximal intestinal diversion is associated with increased morbidity in patients undergoing elective colectomy for diverticular disease: an ACS-NSQIP study."
04/01/2013 - "The purpose of this study is to directly compare outcomes of SIL sigmoid colectomy for diverticular disease with standard multiport laparoscopic (LAP) technique. "

07/31/2023 - "Diverticular disease (DD) management is impaired by its pathogenesis, which is still not completely defined, with an unmet clinical need for improved therapies. "
11/28/2010 - "To evaluate the efficacy of endoscopic diagnosis and therapy for jejunal diverticular bleeding. "
08/01/2011 - "The aim of this multicentric study was to evaluate the disease specific and the generic quality of life in patients affected by colonic diverticular disease (DD) who had undergone minimally invasive or open colonic resection or who had been treated with medical therapy in the long-term follow-up. "
04/01/1999 - "Laparoscopic surgery has already begun to influence the management of diverticular disease, but the randomized controlled trials needed to support therapy decisions are largely missing."
12/01/2023 - "Barium enema: Compassionate therapy for refractory colonic diverticular bleeding?"

11/01/2022 - "Background and study aims  Endoscopic band ligation (EBL) has been reported to be effective for colorectal diverticular bleeding. "
01/01/2016 - "Endoscopic Band Ligation: A Safe And Effective Treatment For Active Diverticular Bleeding."
01/01/2004 - "Diverticular bleeding: novel treatment with band ligation."
01/01/2021 - "Comparison of endoscopic band ligation devices used for colonic diverticular bleeding: in vivo animal study."
08/04/2020 - "The aim of this study is to compare the bowel-specific quality of life and functional outcomes between these 2. Between June 2015 and February 2019, patients were randomly assigned to inferior mesenteric artery low ligation or inferior mesenteric artery preservation during elective laparoscopic sigmoidectomy for diverticular disease. "

11/20/2023 - "Colonic diverticular bleeding (CDB) is the most common cause of ALGIB, and endoscopic hemostasis is an effective treatment for massive CDB. "
01/01/2023 - "Emergency endoscopic hemostasis for colonic diverticular bleeding is effective in preventing serious consequences. "
09/15/2023 - "This study aimed to investigate the risk factors for difficult endoscopic hemostasis in patients with colonic diverticular bleeding and to evaluate the efficacy and safety of transcatheter arterial embolization (TAE) for colonic diverticular bleeding. "
01/01/2018 - "This study aimed to examine whether endoscopic visibility of colonic diverticular bleeding affects the risk of rebleeding after endoscopic hemostasis. "
09/15/2023 - "Risk factors for difficult endoscopic hemostasis for colonic diverticular bleeding and efficacy and safety of transcatheter arterial embolization."

03/01/2021 - "Traditionally, management of complicated diverticular disease has involved open damage control operations with large definitive resections and colostomies. "
03/01/2020 - "However, there is moderate to low agreement regarding the use of a minimally invasive approach in patients with perforated diverticular disease (Hinchey III/IV), as well as primary anastomosis is still feared too risky versus end colostomy. "
07/01/2018 - "Current Options for the Emergency Management of Diverticular Disease and Options to Reduce the Need for Colostomy."
01/01/2017 - "We describe a patient successfully managed with on-table endoscopy and, under local anaesthetic, the formation of a left iliac fossa trephine loop colostomy, permitting an enterolithotomy to deliver the stone whilst accommodating for severe pre-existing distal sigmoid diverticular disease. "
12/01/2015 - "Almost all (42) had a colostomy and most (28) had a history of stoma creation due to diverticular disease. "