Talipes Cavus (Pes Cavus)

A foot deformity in which the arch of the foot is high and often the heel adducted.

Also Known As:

Pes Cavus; Cavovarus Foot Deformity; Cavus Foot; High-Arched Foot; Cavovarus Foot Deformities; Cavus Deformities; Foot Deformities, Cavovarus; Foot Deformity, Cavovarus; High Arched Foot; Cavus Deformity

Networked: 141 relevant articles (6 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pain (Aches)
2.	Congenital Abnormalities (Deformity)
3.	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
4.	Hallux Valgus
5.	Rheumatoid Arthritis

Experts

1.	Burns, Joshua: 5 articles (01/2014 - 05/2006)
2.	Frattini, Daniele: 3 articles (10/2021 - 06/2009)
3.	Fusco, Carlo: 3 articles (10/2021 - 06/2009)
4.	Myerson, Mark S: 3 articles (06/2019 - 01/2005)
5.	Wolfe, Joshua: 2 articles (07/2021 - 07/2021)
6.	Aronow, Michael S: 2 articles (03/2014 - 03/2002)
7.	Wenz, W: 2 articles (03/2014 - 03/2000)
8.	Najafi, Bijan: 2 articles (01/2014 - 06/2012)
9.	Wrobel, James S: 2 articles (01/2014 - 06/2012)
10.	Weiner, Dennis S: 2 articles (12/2013 - 01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Talipes Cavus:

1.	Lactic Acid (Lactate)FDA LinkGeneric 07/01/1989 - "With oral administration of thiamine hydrochloride (1000 mg) and high fat diet (60-70%), muscle weakness improved, and lactate and pyruvate levels in the serum reduced to normal ranges, whereas the mental deterioration, muscle atrophy, pes cavus progressed very slowly. "
2.	Pyruvic Acid (Pyruvate)IBA 07/01/1989 - "With oral administration of thiamine hydrochloride (1000 mg) and high fat diet (60-70%), muscle weakness improved, and lactate and pyruvate levels in the serum reduced to normal ranges, whereas the mental deterioration, muscle atrophy, pes cavus progressed very slowly. "
3.	thiamine hydrochloride FDA LinkGeneric 07/01/1989 - "With oral administration of thiamine hydrochloride (1000 mg) and high fat diet (60-70%), muscle weakness improved, and lactate and pyruvate levels in the serum reduced to normal ranges, whereas the mental deterioration, muscle atrophy, pes cavus progressed very slowly. "
4.	salicylhydroxamic acid (SHAM)IBA 05/01/2006 - "In a randomized, single-blind, sham-controlled trial, the effect of custom foot orthoses on foot pain, function, quality of life, and plantar pressure loading in people with a cavus foot type was investigated. " 10/17/2007 - "In one randomised controlled trial, custom-made foot orthoses were significantly more beneficial than sham orthoses for treating chronic musculoskeletal foot pain associated with pes cavus in a variety of clinical populations. " 05/01/2009 - "Compared with placebo or sham, custom-made foot orthoses modestly reduce foot pain from pes cavus (high arch), arthritis, plantar fasciitis, and painful hallux valgus. "
5.	SolutionsIBA 06/01/2012 - "This study suggests that painful Pes Cavus alters the shape of probability distribution of plantar loading during walking and CFO are an effective therapeutic solution that can significantly improve it. " 09/01/2010 - "First ray dorsiflexion osteotomy combined with tendon transfers is a good and consistent solution to realign the foot and provides short-term to mid-term satisfactory results in 90% of patients with a rigid forefoot cavus deformity due to plantar flexion of the first ray and with a still passively reducible tarsus."
6.	Myelin P0 Protein (Myelin Protein Zero)IBA 06/01/2010 - "Neurologic examination revealed pes cavus, and motor nerve conduction studies were consistent with Charcot-Marie-Tooth disease type 1. Genetic testing later showed the presence of a novel frameshift mutation within the transmembrane domain of the myelin protein zero gene (Leu144fs). "
7.	Botulinum Toxins (Botulinum Toxin)IBA 08/01/2010 - "Randomized trial of botulinum toxin to prevent pes cavus progression in pediatric Charcot-Marie-Tooth disease type 1A."
8.	ethyleneIBA 12/01/2022 - "The aim of this study was to compare the plantar pressure distribution while walking in the same footwear in three different situations: with an original footwear insole, with an ethylene-vinyl acetate customized insole, and with a 3D printed anatomical insole to find out the optimal insoles for people with a normal, flat, and high arched foot according to the plantar pressure relief. "
9.	vinyl acetateIBA 12/01/2022 - "The aim of this study was to compare the plantar pressure distribution while walking in the same footwear in three different situations: with an original footwear insole, with an ethylene-vinyl acetate customized insole, and with a 3D printed anatomical insole to find out the optimal insoles for people with a normal, flat, and high arched foot according to the plantar pressure relief. "
10.	Adenosine Triphosphatases (ATPase)IBA 02/01/2018 - "Cerebellar ataxia, areflexia, pes cavus, optic atrophy and sensorineural hearing impairment (CAPOS) is a rare clinically distinct syndrome caused by a single dominant missense mutation, c.2452G>A, p.Glu818Lys, in ATP1A3, encoding the neuron-specific alpha subunit of the Na+/K+-ATPase α3. " 12/01/2015 - "ATP1A3, the gene encoding the α3-subunit of the Na(+) /K(+) -ATPase pump, has been involved in four clinical neurological entities: (1) alternating hemiplegia of childhood (AHC); (2) rapid-onset dystonia parkinsonism (RDP); (3) CAPOS (cerebellar ataxia, areflexia, pes cavus, optic atrophy, sensorineural hearing loss) syndrome; and (4) early infantile epileptic encephalopathy. "

Therapies and Procedures

1.	Osteotomy 10/26/2019 - "To assess the efficacy of soft tissue release combined with joint-sparing osteotomy in the treatment of cavovarus foot deformity in older children. " 12/01/2023 - "This article presents the operative technique for percutaneous cavus foot correction including a lateralizing calcaneal osteotomy and proximal first ray osteotomy. " 12/01/2023 - "Supramalleolar Osteotomies in Cavovarus Foot Deformity: Why Patient-Specific Instruments Make a Difference." 04/01/2022 - "Closing wedge midfoot osteotomy to correct anterior pes cavus may be an interesting indication to use customized 3D printed surgical guides." 04/01/2022 - "Technique tip: 3D printing surgical guide for pes cavus midfoot osteotomy."
2.	Foot Orthoses 02/02/2023 - "The aim of the study is to achieve greater insight into the balance and athlete position during the CrossFit training by means of inertial sensors, with a particular focus on the role of different custom foot orthoses (CFOs) in order to detect correlations with the role of the cavus foot. " 06/01/2012 - "Dynamic plantar loading index: understanding the benefit of custom foot orthoses for painful pes cavus." 01/01/1993 - "While treatment of the cavus foot with orthotic shoe inserts is sometimes worthwhile, the clinician should be aware of limited success in this instance. " 05/01/2006 - "In conclusion, custom foot orthoses are more effective than a control for the treatment of cavus foot pain and its associated limitation in function." 05/01/2006 - "Custom foot orthoses are widely prescribed to treat cavus foot pain. "
3.	Arthrodesis 07/01/2021 - "Ankle and Pantalar Arthrodesis: End-Stage Salvage in Cavus Foot." 07/01/2021 - "Principles of Triple Arthrodesis and Limited Arthrodesis in the Cavus Foot." 12/01/2013 - "When the cavus foot has become rigid, midfoot and triple arthrodesis may be the only reasonable surgical options left. " 12/01/2013 - "Arthrodesis for the cavus foot: when, where, and how?" 04/01/2006 - "[Historical development of arthrodesis of pes cavus]."
4.	Tenotomy 06/26/2022 - "Soft-tissue release, tendon-transfer, and bony reconstruction are commonly used to correct cavus foot. " 01/01/1976 - "Peroneus longus tendon lengthening as an adjuvant measure in cavus foot surgery." 01/01/1984 - "In the child between 4 and 12 years of age presenting with cavus deformity associated with spastic cerebral palsy, symptomatic feet may be improved by soft tissue release of plantar structures followed by appropriate tendon lengthenings or transfers and good cast correction. " 01/01/1977 - "Described is a surgical procedure for pes cavus which includes multiple osteotomies of the metatarsals, usually combined with Steindler fasciotomy and extensor tenotomy. "
5.	Oral Administration 07/01/1989 - "With oral administration of thiamine hydrochloride (1000 mg) and high fat diet (60-70%), muscle weakness improved, and lactate and pyruvate levels in the serum reduced to normal ranges, whereas the mental deterioration, muscle atrophy, pes cavus progressed very slowly. "