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TP421
has antineoplastic activity; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrans: 130
Benzopyrans: 195
Coumarins: 826
TP421: 1
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzopyrans: 195
Coumarins: 826
TP421: 1
Organic Chemicals: 133
Organophosphorus Compounds: 300
TP421: 1
Experts
1.
Millard, Melissa
: 1 article (01/2013)
2.
Neamati, Nouri
: 1 article (01/2013)
3.
Shabaik, Yumna H
: 1 article (01/2013)
Related Diseases
1.
Pancreatic Neoplasms (Pancreatic Cancer)
01/01/2013 - "
TP421 is a representative compound of a new promising class of mitochondrial-targeted agents useful for pancreatic cancer treatment.
"
01/01/2013 - "
TP421 exhibited sub-micromolar IC(50) values in all the pancreatic cancer cell lines tested using MTT and colony formation assays.
"