N- (adamantan- 1- yl)- 4- oxo- 1- pentyl- 6- phenyl- 1,4- dihydroquinoline- 3- carboxamide

structure in first source

Also Known As:

COR167

Networked: 5 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Adamantane: 182
        N-(adamantan-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide: 5
    - Bridged-Ring Compounds: 1
      - Adamantane: 182
        N-(adamantan-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide: 5
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        N-(adamantan-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide: 5

Experts

1.	Corelli, Federico: 4 articles (01/2019 - 06/2012)
2.	Mugnaini, Claudia: 4 articles (01/2019 - 06/2012)
3.	Annunziata, Pasquale: 2 articles (01/2019 - 01/2017)
4.	Cioni, Chiara: 2 articles (01/2019 - 01/2017)
5.	Pasquini, Serena: 2 articles (12/2012 - 06/2012)
6.	Marotta, Giuseppe: 1 article (01/2019)
7.	Tassi, Maristella: 1 article (01/2019)
8.	Aldinucci, Carlo: 1 article (12/2012)
9.	Contartese, Antonella: 1 article (12/2012)
10.	Frosini, Maria: 1 article (12/2012)

Related Diseases

1.	Peripheral Nervous System Diseases (PNS Diseases) 05/26/2023 - "The aim of this study was to evaluate the anti-neuropathic activity of a novel selective CB2 agonist, COR167, in a preclinical model of peripheral neuropathy, the spared nerve injury (SNI). " 05/26/2023 - "The Selective CB2 Agonist COR167 Reduced Symptoms in a Mice Model of Trauma-Induced Peripheral Neuropathy through HDAC-1 Inhibition."
2.	Wounds and Injuries (Trauma) 05/26/2023 - "The Selective CB2 Agonist COR167 Reduced Symptoms in a Mice Model of Trauma-Induced Peripheral Neuropathy through HDAC-1 Inhibition."
3.	Ischemia 12/01/2012 - "The aim of this study was to investigate the potential protection of brain tissues afforded by the novel substituted 4-quinolone-3-carboxylic acid derivative COR167, a selective CB2 agonist, toward ischemia and reperfusion-induced injury, as well as the mechanism of this potential effect. "
4.	Relapsing-Remitting Multiple Sclerosis 01/01/2017 - "COR167, a novel CB2-selective high affinity agonist, was found to significantly inhibit, in a dose-dependent manner, the proliferation of both peripheral blood mononuclear cells and myelin basic protein-reactive T cell lines from normal healthy subjects and patients with relapsing-remitting multiple sclerosis (MS). "
5.	Reperfusion Injury 12/01/2012 - "A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury." 12/01/2012 - "The CB2 receptor agonist COR167 potently protected rat brain cortical slices against OGD and reperfusion injury, partly through CB2 receptors activation."

Related Drugs and Biologics

1.	4-quinolone-3-carboxylic acid
2.	CB2 Cannabinoid Receptor
3.	Cannabinoids
4.	Formaldehyde (Formol)
5.	Myelin Basic Protein

Related Therapies and Procedures

1.	Oral Administration