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ayanin diacetate

has antineoplastic activity; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        ayanin diacetate: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        ayanin diacetate: 1

Experts

1.	Estévez, Francisco: 1 article (11/2012)
2.	Estévez, Sara: 1 article (11/2012)
3.	León, Francisco: 1 article (11/2012)
4.	López, Mariana: 1 article (11/2012)
5.	Marrero, María Teresa: 1 article (11/2012)
6.	Negrín, Gledy: 1 article (11/2012)
7.	Pérez, Francisco J: 1 article (11/2012)
8.	Quintana, José: 1 article (11/2012)
9.	Triana, Jorge: 1 article (11/2012)

Related Diseases

1.

11/09/2012 - "Ayanin diacetate-induced cell death is amplified by TRAIL in human leukemia cells."
11/09/2012 - "Here we demonstrate that the semi-synthetic flavonoid ayanin diacetate induces cell death selectively in leukemia cells without affecting the proliferation of normal lymphocytes. "
11/09/2012 - "Incubation of human leukemia cells with ayanin diacetate induced G(2)-M phase cell cycle arrest and apoptosis which was prevented by the non-specific caspase inhibitor z-VAD-fmk and reduced by the overexpression of Bcl-x(L). "

Related Drugs and Biologics

1.	Caspases
2.	Flavonoids
3.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone