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diazabicyclo(2.2.2)octane

structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclooctanes: 4
        diazabicyclo(2.2.2)octane: 3
- Aza Compounds: 3
  - diazabicyclo(2.2.2)octane: 3

Experts

1.	Chen, Ravit: 1 article (10/2019)
2.	Columbus, Ishay: 1 article (10/2019)
3.	Dagan, Shai: 1 article (10/2019)
4.	Elias, Shlomi: 1 article (10/2019)
5.	Fridkin, Gil: 1 article (10/2019)
6.	Karton-Lifshin, Naama: 1 article (10/2019)
7.	Katalan, Shahaf: 1 article (10/2019)
8.	Madmon, Moran: 1 article (10/2019)
9.	Yehezkel, Lea: 1 article (10/2019)
10.	Zafrani, Yossi: 1 article (10/2019)

Related Diseases

1.	Photosensitivity Disorders (Photodermatitis) 05/24/2007 - "It is shown that 1,4-diazabicyclo[2.2.2]octane (DABCO) does not enhance radiative properties of the dimol species generated by the photosensitization. "
2.	Paralysis (Palsy) 01/01/2016 - "We evaluated the impact of these activities on the efficiency of virus inactivation and found: i) the synergism between membranolytic and chaotropic-like activities is sufficient for the inactivation of enveloped viruses (influenza A, encephalitis, vaccinia viruses) for 1,4-diazabicyclo [2.2.2]octane based aRNases, ii) the inactivation of non-enveloped viruses (encephalomyocarditis, acute bee paralysis viruses) is totally dependent on the synergism of chaotropic-like and ribonuclease activities, iii) ribonuclease activity plays a leading role in the inactivation of RNA viruses by aRNases Dp12F6, Dtr12 and K-D-1, iv) peptide-like aRNases (L2-3, K-2) being effective virus killers have a more specific mode of action. "
3.	Human Influenza (Influenza) 01/01/2016 - "We evaluated the impact of these activities on the efficiency of virus inactivation and found: i) the synergism between membranolytic and chaotropic-like activities is sufficient for the inactivation of enveloped viruses (influenza A, encephalitis, vaccinia viruses) for 1,4-diazabicyclo [2.2.2]octane based aRNases, ii) the inactivation of non-enveloped viruses (encephalomyocarditis, acute bee paralysis viruses) is totally dependent on the synergism of chaotropic-like and ribonuclease activities, iii) ribonuclease activity plays a leading role in the inactivation of RNA viruses by aRNases Dp12F6, Dtr12 and K-D-1, iv) peptide-like aRNases (L2-3, K-2) being effective virus killers have a more specific mode of action. "
4.	Encephalitis (Encephalitis, Rasmussen) 01/01/2016 - "We evaluated the impact of these activities on the efficiency of virus inactivation and found: i) the synergism between membranolytic and chaotropic-like activities is sufficient for the inactivation of enveloped viruses (influenza A, encephalitis, vaccinia viruses) for 1,4-diazabicyclo [2.2.2]octane based aRNases, ii) the inactivation of non-enveloped viruses (encephalomyocarditis, acute bee paralysis viruses) is totally dependent on the synergism of chaotropic-like and ribonuclease activities, iii) ribonuclease activity plays a leading role in the inactivation of RNA viruses by aRNases Dp12F6, Dtr12 and K-D-1, iv) peptide-like aRNases (L2-3, K-2) being effective virus killers have a more specific mode of action. "
5.	Blister (Bulla) 10/25/2019 - "The ability of mono N-methyl-1,4-diazabicyclo[2.2.2]octane fluoride (Me-DABCOF, 1) to act as a bifunctional reagent that effectively and universally neutralizes both the persistent and extremely toxic blister agent HD and the nerve agent VX in nearly neutral aqueous solution, alumina powder or a hydrogel formulation, is described."

Related Drugs and Biologics

1.	Hydrogels
2.	Solutions
3.	Ribonucleases (Ribonuclease)
4.	Powders
5.	Peptides (Polypeptides)
6.	Fluorides
7.	Cross-Linking Reagents
8.	Aluminum Oxide (Sapphire)
9.	Nerve Agents
10.	VX (EDIM)