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tacrine-8-hydroxyquinoline

structure in first source

Also Known As:

IQM-622

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Hydroxyquinolines: 9
        tacrine-8-hydroxyquinoline: 2
  - 3-Ring Heterocyclic Compounds
    - Acridines: 325
      - Aminoacridines: 3
        Tacrine: 772
        tacrine-8-hydroxyquinoline: 2

Experts

1.	Rodríguez-Franco, María Isabel: 2 articles (06/2012 - 07/2010)
2.	Antequera, Desiree: 1 article (06/2012)
3.	Bolos, Marta: 1 article (06/2012)
4.	Carro, Eva: 1 article (06/2012)
5.	Fernandez-Bachiller, María Isabel: 1 article (06/2012)
6.	Ferrer, Isidro: 1 article (06/2012)
7.	Pascual, Consuelo: 1 article (06/2012)
8.	Spuch, Carlos: 1 article (06/2012)
9.	Conde, Santiago: 1 article (07/2010)
10.	Fernández-Bachiller, María Isabel: 1 article (07/2010)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 06/01/2012 - "Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Aβ accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease." 07/08/2010 - "In this work, novel tacrine-8-hydroxyquinoline hybrids have been designed, synthesized, and evaluated as potential multifunctional drugs for the treatment of Alzheimer's disease. " 07/08/2010 - "Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties."
2.	Neurodegenerative Diseases (Neurodegenerative Disease) 06/01/2012 - "Our observations suggest that administration of IQM-622 may have significant beneficial effects in neurodegenerative diseases, including AD, which course with acute or progressive neuronal death."

Related Drugs and Biologics

1.	Cholinergic Agents (Cholinergics)
2.	Copper
3.	Antioxidants