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N,N-didesmethyl-4-hydroxytamoxifen

structure in first source

Also Known As:

norendoxifen

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        Tamoxifen: 14288
        N,N-didesmethyl-4-hydroxytamoxifen: 2

Experts

1.	Ang, Peter Cher Siang: 1 article (01/2016)
2.	Cheung, Yin Bun: 1 article (01/2016)
3.	Chowbay, Balram: 1 article (01/2016)
4.	Dent, Rebecca: 1 article (01/2016)
5.	Lim, Joanne Siok Liu: 1 article (01/2016)
6.	Muerdter, Thomas E: 1 article (01/2016)
7.	Ng, Raymond Chee Hui: 1 article (01/2016)
8.	Schroth, Werner: 1 article (01/2016)
9.	Schwab, Matthias: 1 article (01/2016)
10.	Singh, Onkar: 1 article (01/2016)

Related Diseases

1.

Breast Neoplasms (Breast Cancer)

01/01/2016 - "The aim was to examine the influence of CYP2C19 variants and associated haplotypes on the disposition of tamoxifen and its metabolites, particularly norendoxifen (NorEND), in Asian patients with breast cancer. "
01/01/2016 - "Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients."
06/13/2013 - "The affinities of both isomers for aromatase and the estrogen receptors, as well as the pharmacokinetic results, support the further development of norendoxifen and its analogues for breast cancer treatment."

Related Drugs and Biologics

1.	Cytochrome P-450 CYP2C19
2.	Tamoxifen
3.	Estrogen Receptors
4.	Aromatase (CYP19)