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2- (4- ((4- (6- methoxy- 3- pyridinyl)- 5- (4- (trifluoromethoxy)phenyl)- 2- thiazolyl)methoxy)- 2- methylphenoxy)acetic acid

structure in first source

Also Known As:

NVS001

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - 2-(4-((4-(6-methoxy-3-pyridinyl)-5-(4-(trifluoromethoxy)phenyl)-2-thiazolyl)methoxy)-2-methylphenoxy)acetic acid: 1
- Sulfur Compounds: 278
  - Thiazoles: 392
    - 2-(4-((4-(6-methoxy-3-pyridinyl)-5-(4-(trifluoromethoxy)phenyl)-2-thiazolyl)methoxy)-2-methylphenoxy)acetic acid: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Acetates: 4994
      - 2-(4-((4-(6-methoxy-3-pyridinyl)-5-(4-(trifluoromethoxy)phenyl)-2-thiazolyl)methoxy)-2-methylphenoxy)acetic acid: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - 2-(4-((4-(6-methoxy-3-pyridinyl)-5-(4-(trifluoromethoxy)phenyl)-2-thiazolyl)methoxy)-2-methylphenoxy)acetic acid: 1

Experts

1.	Buono, Chiara: 1 article (03/2012)
2.	Busch, Steve: 1 article (03/2012)
3.	Chibout, Salah-Dine: 1 article (03/2012)
4.	Cruz, Elba: 1 article (03/2012)
5.	Gurnani, Maya: 1 article (03/2012)
6.	McLean, Lee Anne: 1 article (03/2012)
7.	Moulin, Pierre: 1 article (03/2012)
8.	Patel, Parul: 1 article (03/2012)
9.	Pognan, Francois: 1 article (03/2012)
10.	Reising, Albert: 1 article (03/2012)

Related Diseases

1.	Cataract (Cataracts) 03/01/2012 - "Lens explant cultures were used to assess the mechanism of drug-induced cataractogenic potential of NVS001, a peroxisome proliferator-activated receptor delta (PPARδ) agonist, which resulted in cataract in all treated animals during a 13-week rat study. "
2.	Rupture 03/01/2012 - "NVS001 and ciglitazone had comparable cataractogenic effects after 48 h with histology showing rupture of the lens capsule, lens fiber degeneration, cortical lens vacuolation, and lens epithelial degeneration. "

Related Drugs and Biologics

1.	PPAR delta
2.	Capsules (Microcapsules)
3.	ciglitazone