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2G-NN16

inhibits Tc17 differentiation of CD8+ T lymphocytes; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	de la Mata, F Javier: 2 articles (06/2014 - 10/2010)
2.	Corbí, Angel L: 1 article (06/2014)
3.	Domínguez-Soto, Angeles: 1 article (06/2014)
4.	Gomez, Rafael: 1 article (06/2014)
5.	Jiménez, José Luis: 1 article (06/2014)
6.	Muñoz-Fernandez, María Ángeles: 1 article (06/2014)
7.	Perisé-Barrios, Ana Judith: 1 article (06/2014)
8.	Clemente, María Isabel: 1 article (10/2010)
9.	García, Dolores: 1 article (10/2010)
10.	Gómez, Rafael: 1 article (10/2010)

Related Diseases

1.	HIV Infections (HIV Infection) 06/28/2014 - "Carbosilane dendrimers 2G-NN16 and 2G-03NN24 can be used as efficient non-viral vectors for gene therapy applications, mainly in the treatment of HIV infection. "
2.	Astrocytoma (Pilocytic Astrocytoma) 10/01/2010 - "There was no cytotoxicity in HIV-infected or non-infected human astrocytoma cells when treated with up to 24 microg/mL of 2G-NN16 dendrimer or siRNA/2G-NN16 dendriplexes, and siRNA/2G-NN16 dendriplexes were seen to successfully transfect human astrocytes even after crossing an in vitro BBB model. " 10/01/2010 - "We tested the cytotoxicity in human astrocytoma cells caused by 2G-NN16 and dendriplexes formed with siRNA (siRNA/2G-NN16) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium-bromide (MTT) and lactate dehydrogenase assays. "

Related Drugs and Biologics

1.	Dendrimers (Dendrons)
2.	Small Interfering RNA (siRNA)
3.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)
4.	carbosilane
5.	2G-03NN24