HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

5- (3- ethyl- 1,2,4- oxadiazol- 5- yl)- 1,4,5,6- tetrahydropyrimidine

structure in first source

Also Known As:

CDD-0102A

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - Oxadiazoles: 146
        5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine: 4
  - Pyrimidines: 510
    - 5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine: 4

Experts

1.	Messer, William S: 3 articles (12/2022 - 08/2002)
2.	Ragozzino, Michael E: 2 articles (12/2022 - 03/2012)
3.	Athnaiel, Onella: 1 article (12/2022)
4.	Job, Greeshma A: 1 article (12/2022)
5.	Ocampo, Roberto: 1 article (12/2022)
6.	Teneqexhi, Pamela: 1 article (12/2022)
7.	Artis, Sonja: 1 article (03/2012)
8.	Beck, Joseph E: 1 article (03/2012)
9.	Singh, Amritha: 1 article (03/2012)
10.	Twose, Trevor M: 1 article (03/2012)

Related Diseases

1.	Nervous System Diseases (Neurological Disorders) 03/01/2012 - "Salivation increased with dose, and the estimated ED(50) was 2.0 mg/kg. The data suggest that CDD-0102A has unique memory and cognitive enhancing properties that might be useful in the treatment of neurological disorders at doses that do not produce adverse effects such as salivation."
2.	Autistic Disorder (Autism) 12/01/2022 - "The present experiments examined whether the partial M1 muscarinic receptor agonist, 5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine hydrochloride (CDD-0102A), alleviates behavioral flexibility deficits and/or stereotyped motor behaviors in the BTBR mouse model of autism. " 12/01/2022 - "Effects of the Partial M1 Muscarinic Cholinergic Receptor Agonist CDD-0102A on Stereotyped Motor Behaviors and Reversal Learning in the BTBR Mouse Model of Autism." 01/01/2023 - "The Partial M1 Muscarinic Cholinergic Receptor Agonist, CDD-0102A, Differentially Modulates Glutamate Efflux in Striatal Subregions during Stereotyped Motor Behavior in the BTBR Mouse Model of Autism."
3.	Alzheimer Disease (Alzheimer's Disease) 08/01/2002 - "5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine (CDD-0102) is a potent M1 agonist with a low side effect profile that enhances memory function in animal models of Alzheimer's disease. "

Related Drugs and Biologics

1.	Cholinergic Agents (Cholinergics)
2.	Cholinergic Receptors
3.	Muscarinic M1 Receptor
4.	Glutamic Acid (Glutamate)