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4-O-decyl-gabosine D

inhibits glutathione-S-transferase M1; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Cyclohexanones: 5
    - 4-O-decyl-gabosine D: 1
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclohexanes: 3
        Cyclohexanones: 5
        4-O-decyl-gabosine D: 1

Experts

1.	Chang, Hui Chuan: 1 article (12/2011)
2.	Cheng, Hau M: 1 article (12/2011)
3.	Jao, Shu-Chuan: 1 article (12/2011)
4.	Li, Wen-Shan: 1 article (12/2011)
5.	Lu, I-Hsuan: 1 article (12/2011)
6.	Shing, Tony K M: 1 article (12/2011)
7.	Wang, Chie-Hong: 1 article (12/2011)
8.	Wu, Ho T: 1 article (12/2011)
9.	Yen, Tien-Jui: 1 article (12/2011)

Related Diseases

1.	Adenocarcinoma of Lung 12/22/2011 - "The results of this effort show that the lead 4-O-decyl-gabosine D (24) has optimum synergetic effect in A549 human lung adenocarcinoma epithelial cell and that this activity involves inhibition of glutathione S-transferase M1, apparently consistent with siRNA-mediated knockdown of GSTM1 gene."

Related Drugs and Biologics

1.	Small Interfering RNA (siRNA)
2.	glutathione S-transferase M1