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3,3',7-trihydroxy-4'-methoxyflavon

a potent inhibitor of SIK2; structure in first source

Also Known As:

4'-O-methylfisetin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        3,3',7-trihydroxy-4'-methoxyflavon: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        3,3',7-trihydroxy-4'-methoxyflavon: 1

Experts

1.	Hirata, Yoshiyuki: 1 article (01/2011)
2.	Horike, Nanao: 1 article (01/2011)
3.	Itoh, Yumi: 1 article (01/2011)
4.	Kawahara, Hidehisa: 1 article (01/2011)
5.	Kitagawa, Kazuo: 1 article (01/2011)
6.	Kumagai, Ayako: 1 article (01/2011)
7.	Nagaoka, Yasuo: 1 article (01/2011)
8.	Sasaki, Tsutomu: 1 article (01/2011)
9.	Satoh, Yudai: 1 article (01/2011)
10.	Takemori, Hiroshi: 1 article (01/2011)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 01/01/2011 - "Thus, we decided to synthesize 4'-O-methylfisetin (4'MF) and found that 4'MF strongly induced melanogenesis in B16F10 melanoma cells, which was accompanied by the nuclear translocation of TORC1, and the 4'-O-methylfisetin-induced melanogenic programs were inhibited by the overexpression of dominant negative TORC1. "

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