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2- quinoxaline- carboxamide- N- adamantan- 1- yl

structure in first source

Also Known As:

NPS 2390; NPS-2390; NPS2390

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Adamantane: 182
        2-quinoxaline-carboxamide-N-adamantan-1-yl: 3
    - Bridged-Ring Compounds: 1
      - Adamantane: 182
        2-quinoxaline-carboxamide-N-adamantan-1-yl: 3
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinoxalines: 324
      - 2-quinoxaline-carboxamide-N-adamantan-1-yl: 3

Experts

1.	Mo, Lianjie: 1 article (01/2017)
2.	Song, Zhengfei: 1 article (01/2017)
3.	Wan, Yingfeng: 1 article (01/2017)
4.	Wang, Kun: 1 article (01/2017)
5.	Wang, Yirong: 1 article (01/2017)
6.	Xue, Zhaoliang: 1 article (01/2017)
7.	Bai, Shu-Zhi: 1 article (03/2011)
8.	Guo, Jin: 1 article (03/2011)
9.	Hao, Jing-Hui: 1 article (03/2011)
10.	Li, Guang-Wei: 1 article (03/2011)

Related Diseases

1.	Brain Edema (Cerebral Edema) 01/01/2017 - "Our data indicated that NPS2390 significantly reduced the brain edema and improved the neurological function after TBI. "
2.	Wounds and Injuries (Trauma) 07/15/2010 - "On the other hand, mechanical injury produced an [Ca(2+)](i) wave propagation that was partially inhibited by siRNA-CaSR, NPS2390 and the extracellular Ca(2+) chelator EGTA, which suggest a link of CaSR between cell-cell communication and wound repair in differentiated HBEC. " 07/15/2010 - "Furthermore, U73122 (an inhibitor of phospholipase C (PLC)) and PD 98059 (an inhibitor of ERK1/2) as well as siRNA-CaSR and NPS2390 partially inhibited wound repair and HBEC proliferation. "
3.	Hypoxia (Hypoxemia) 03/01/2011 - "GdCl(3) (an agonist of CaSR) or NPS2390 (an antagonist of CaSR) amplified or weakened the effect of hypoxia, respectively. "
4.	Traumatic Brain Injuries (Traumatic Brain Injury) 01/01/2017 - "Calcium-sensing receptor antagonist NPS2390 attenuates neuronal apoptosis though intrinsic pathway following traumatic brain injury in rats."

Related Drugs and Biologics

1.	Calcium-Sensing Receptors
2.	Small Interfering RNA (siRNA)
3.	Type C Phospholipases
4.	Egtazic Acid (EGTA)
5.	Chelating Agents
6.	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- one
7.	1- (6- ((3- methoxyestra- 1,3,5(10)- trien- 17- yl)amino)hexyl)- 1H- pyrrole- 2,5- dione