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5-ethyl-1-phenyl-2-(1H) pyridone

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridones: 14
      - 5-ethyl-1-phenyl-2-(1H) pyridone: 2

Experts

1.	Giri, Shri N: 2 articles (01/2010 - 01/2010)
2.	Grattendick, Ken J: 2 articles (01/2010 - 01/2010)
3.	Nakashima, James M: 2 articles (01/2010 - 01/2010)

Related Diseases

1.

Septic Shock (Toxic Shock Syndrome)

01/01/2010 - "The aim of this study was to determine if a novel compound, 5-ethyl-1-phenyl-2-(1H) pyridone (5-EPP), could decrease the increased serum levels of various biomarkers of MOD in LPS/D-Galactosamine (LPS/D-GalN) and cecal ligation and puncture (CLP) models of septic shock in mice. "
01/01/2010 - "The aim of this study was to determine if a novel compound, 5-ethyl-1-phenyl-2-(1H) pyridone (5-EPP), could decrease the increased serum levels of various biomarkers of MOD in LPS/D-Galactosamine (LPS/D-GalN) and cecal ligation and puncture (CLP) models of septic shock in mice. "
01/01/2010 - "Effects of 5-ethyl-1-phenyl-2-(1H) pyridone on serum biomarkers of multiorgan dysfunction and mortality in lipopolysaccharide/glactosamine and cecal ligation and puncture models of septic shock in mice."
01/01/2010 - "Effects of 5-ethyl-1-phenyl-2-(1H) pyridone on serum biomarkers of multiorgan dysfunction and mortality in lipopolysaccharide/galactosamine and cecal ligation and puncture models of septic shock in mice."

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	Galactosamine
3.	Lipopolysaccharides

Related Therapies and Procedures

1.	Punctures
2.	Ligation