Autosomal Recessive Spastic Paraplegia 39

mutation in PNPLA6

Also Known As:

Spastic Paraplegia 39, Autosomal Recessive; NTE-Related Motor Neuron Disorder; NTEMND; SPG39

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Motor Neuron Disease (Primary Lateral Sclerosis)
2.	Hereditary Spastic Paraplegia

Drugs and Important Biological Agents (IBA) related to Autosomal Recessive Spastic Paraplegia 39:

1.	Phospholipases (Phospholipase)IBA 03/01/2013 - "Mutations in patatin-like phospholipase domain containing 6 (PNPLA6), also known as neuropathy target esterase (NTE) or SPG39, cause hereditary spastic paraplegia (HSP). "
2.	EsterasesIBA 07/01/2010 - "Recently, mutations within the esterase domain of NTE were identified in patients with a novel type of HSP (SPG39) designated NTE-related motor neuron disease (NTE-MND). "
3.	neurotoxic esteraseIBA 03/01/2013 - "Mutations in patatin-like phospholipase domain containing 6 (PNPLA6), also known as neuropathy target esterase (NTE) or SPG39, cause hereditary spastic paraplegia (HSP). "