HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

MAST Syndrome

mutation in ACP33

Also Known As:

Spastic Paraplegia 21, Autosomal Recessive

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Nervous System Diseases: 14178
Mental Disorders: 24177
- Neurocognitive Disorders: 1448
  - Dementia: 38184
    - MAST Syndrome: 2
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Nervous System Malformations: 35
    - Hereditary Sensory and Motor Neuropathy: 249
      - Hereditary Spastic Paraplegia: 528
        MAST Syndrome: 2
- Inborn Genetic Diseases: 11939
  - Nervous System Heredodegenerative Disorders: 63
    - Hereditary Sensory and Motor Neuropathy: 249
      - Hereditary Spastic Paraplegia: 528
        MAST Syndrome: 2

Related Diseases

1.	Hereditary Spastic Paraplegia

Experts

1.	Bivona, Alexis: 1 article (01/2016)
2.	Cheriyath, Venugopalan: 1 article (01/2016)
3.	Davenport, Anne: 1 article (01/2016)
4.	Latson, Will: 1 article (01/2016)
5.	Lemanski, Larry F: 1 article (01/2016)
6.	Bozzolan, Françoise: 1 article (07/2012)
7.	Chertemps, Thomas: 1 article (07/2012)
8.	Durand, Nicolas: 1 article (07/2012)
9.	Maria, Annick: 1 article (07/2012)
10.	Maïbèche-Coisne, Martine: 1 article (07/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to MAST Syndrome:

1.	Proteins (Proteins, Gene)FDA Link 01/01/2016 - "Mast syndrome, an autosomal recessive, progressive form of hereditary spastic paraplegia, is associated with mutations in SPG21 loci that encode maspardin protein. " 07/01/2012 - "Mast syndrome is a complicated form of human hereditary spastic paraplegias, caused by a mutation in the gene acid cluster protein 33, which encodes a protein designated as "maspardin." Maspardin presents similarity to the α/β-hydrolase superfamily, but might lack enzymatic activity and rather be involved in protein-protein interactions. "
2.	HydrolasesIBA 07/01/2012 - "Mast syndrome is a complicated form of human hereditary spastic paraplegias, caused by a mutation in the gene acid cluster protein 33, which encodes a protein designated as "maspardin." Maspardin presents similarity to the α/β-hydrolase superfamily, but might lack enzymatic activity and rather be involved in protein-protein interactions. "
3.	AcidsIBA 07/01/2012 - "Mast syndrome is a complicated form of human hereditary spastic paraplegias, caused by a mutation in the gene acid cluster protein 33, which encodes a protein designated as "maspardin." Maspardin presents similarity to the α/β-hydrolase superfamily, but might lack enzymatic activity and rather be involved in protein-protein interactions. "