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Type 6 MODY

Also Known As:

MODY, Type 6; MODY6; Maturity-Onset Diabetes of the Young, Type 6

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Glucose Metabolism Disorders: 375
    - Diabetes Mellitus: 56563
      - Type 2 Diabetes Mellitus: 95492
        Type 6 MODY: 5
Endocrine System Diseases: 968
- Diabetes Mellitus: 56563
  - Type 2 Diabetes Mellitus: 95492
    - Type 6 MODY: 5

Related Diseases

1.	Type 3 Maturity-Onset Diabetes of the Young
2.	Hyperglycemia
3.	Type 1 Maturity-Onset Diabetes of the Young
4.	Type 2 Maturity-Onset Diabetes of the Young
5.	Type 4 Maturity-Onset Diabetes of the Young

Experts

1.	Baracco, Bianca: 1 article (10/2021)
2.	Brodosi, Lucia: 1 article (10/2021)
3.	Mantovani, Vilma: 1 article (10/2021)
4.	Pironi, Loris: 1 article (10/2021)
5.	Enya, Mayumi: 1 article (01/2019)
6.	Horikawa, Yukio: 1 article (01/2019)
7.	Goebbels, Sandra: 1 article (04/2010)
8.	Gu, Chunyan: 1 article (04/2010)
9.	Herrera, Pedro: 1 article (04/2010)
10.	Hörnberg, Hanna: 1 article (04/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Type 6 MODY:

1.	Insulin (Novolin)FDA Link 01/01/2019 - "Furthermore, while patients with MODY6 can usually achieve good glycemic control without insulin, when undiagnosed they are prone to become ketotic with chronic hyperglycemia, and microangiopathy can progress. " 10/15/2021 - "However, after the genetic diagnosis of MODY6 and treatment with SUs, he was otherwise able to suspend rapid insulin and close glucose monitoring. " 04/07/2010 - "NeuroD, a transactivator of the insulin gene, is critical for development of the endocrine pancreas, and NeuroD mutations cause MODY6 in humans. " 02/01/2001 - "This form of diabetes can result from mutations in at least seven different genes: hepatocyte nuclear factor(HNF)-4 alpha/MODY1, glucokinase/MODY2, HNF-1 alpha/MODY3, insulin promoter factor(IPF-1)/MODY4, HNF-1 beta/MODY5, NeuroD1/MODY6 and Islet(Isl)-1/MODY7. "
2.	Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)IBA 01/01/2006 - "Mutations of HNF-1alpha (MODY3) and neuroD1/beta2 (MODY6) genes were screened using the single-strand conformation polymorphism (SSCP) technique and sequencing. "
3.	Carboxypeptidase H (Carboxypeptidase E)IBA 01/01/2006 - "The cohort was further characterized by measurement of autoantibodies to carboxypeptidase H (CPH) and SOX13 using radioligand assays, and testing for genetic mutations associated with MODY3/MODY6 and mitochondrial diabetes. "
4.	Trans-Activators (Trans-Acting Factor)IBA 04/07/2010 - "NeuroD, a transactivator of the insulin gene, is critical for development of the endocrine pancreas, and NeuroD mutations cause MODY6 in humans. "
5.	Glucose (Dextrose)FDA LinkGeneric 10/15/2021 - "However, after the genetic diagnosis of MODY6 and treatment with SUs, he was otherwise able to suspend rapid insulin and close glucose monitoring. "
6.	GlucokinaseIBA 02/01/2001 - "This form of diabetes can result from mutations in at least seven different genes: hepatocyte nuclear factor(HNF)-4 alpha/MODY1, glucokinase/MODY2, HNF-1 alpha/MODY3, insulin promoter factor(IPF-1)/MODY4, HNF-1 beta/MODY5, NeuroD1/MODY6 and Islet(Isl)-1/MODY7. "
7.	AutoantibodiesIBA 01/01/2006 - "The cohort was further characterized by measurement of autoantibodies to carboxypeptidase H (CPH) and SOX13 using radioligand assays, and testing for genetic mutations associated with MODY3/MODY6 and mitochondrial diabetes. "

Therapies and Procedures

1.	Glycemic Control 01/01/2019 - "Furthermore, while patients with MODY6 can usually achieve good glycemic control without insulin, when undiagnosed they are prone to become ketotic with chronic hyperglycemia, and microangiopathy can progress. "