Type 8 Maturity-Onset Diabetes of the Young with Exocrine Dysfunction

heterozygous mutation in the CEL gene on chromosome 9q34.

Also Known As:

Maturity-Onset Diabetes of the Young, Type 8, with Exocrine Dysfunction; Diabetes and Pancreatic Exocrine Dysfunction; Diabetes-Pancreatic Exocrine Dysfunction Syndrome

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Glucose Metabolism Disorders: 375
    - Diabetes Mellitus: 56563
      - Type 2 Diabetes Mellitus: 95492
        Type 8 Maturity-Onset Diabetes of the Young with Exocrine Dysfunction: 5
Endocrine System Diseases: 968
- Diabetes Mellitus: 56563
  - Type 2 Diabetes Mellitus: 95492
    - Type 8 Maturity-Onset Diabetes of the Young with Exocrine Dysfunction: 5

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY)
2.	Mason-Type Diabetes
3.	Proteostasis Deficiencies

Experts

1.	Molven, Anders: 5 articles (10/2014 - 09/2008)
2.	Njølstad, Pål R: 5 articles (10/2014 - 09/2008)
3.	Vesterhus, Mette: 4 articles (01/2014 - 09/2008)
4.	Ræder, Helge: 3 articles (01/2014 - 10/2011)
5.	Fjeld, Karianne: 2 articles (10/2014 - 10/2011)
6.	Johansson, Bente B: 2 articles (10/2014 - 10/2011)
7.	Johansson, Stefan: 2 articles (10/2014 - 10/2011)
8.	Saraste, Jaakko: 2 articles (10/2014 - 10/2011)
9.	Torsvik, Janniche: 2 articles (10/2014 - 10/2011)
10.	El Ouaamari, Abdelfattah: 2 articles (01/2014 - 01/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Type 8 Maturity-Onset Diabetes of the Young with Exocrine Dysfunction:

1.	Lipase (Acid Lipase)FDA Link 10/17/2014 - "Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction." 01/01/2014 - "Carboxyl-ester lipase (CEL) maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes and pancreatic exocrine dysfunction due to mutations in the CEL gene encoding CEL. " 01/01/2013 - "Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young)." 10/07/2011 - "Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease." 09/01/2008 - "To further define clinical features associated with the syndrome of diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl-ester lipase (CEL) gene and to assess the effects of pancreatic enzyme substitution therapy. "
2.	EstersIBA 10/17/2014 - "Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction." 01/01/2014 - "Carboxyl-ester lipase (CEL) maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes and pancreatic exocrine dysfunction due to mutations in the CEL gene encoding CEL. " 01/01/2013 - "Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young)." 10/07/2011 - "Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease." 09/01/2008 - "To further define clinical features associated with the syndrome of diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl-ester lipase (CEL) gene and to assess the effects of pancreatic enzyme substitution therapy. "
3.	EnzymesIBA 09/01/2008 - "To further define clinical features associated with the syndrome of diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl-ester lipase (CEL) gene and to assess the effects of pancreatic enzyme substitution therapy. "

Therapies and Procedures

1.	Therapeutics 09/01/2008 - "To further define clinical features associated with the syndrome of diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl-ester lipase (CEL) gene and to assess the effects of pancreatic enzyme substitution therapy. "