Hyperparathyroidism 1

also known as HRPT1; associated with mutations in gene HRPT2 which codes for parafibromin

Also Known As:

Hyperparathyroidism, Familial Isolated Primary; Parathyroid Adenoma, Familial

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Endocrine System Diseases: 968
- Parathyroid Diseases: 240
  - Hyperparathyroidism: 4867
    - Primary Hyperparathyroidism: 4610
      - Hyperparathyroidism 1: 4

Related Diseases

1.	Osteomalacia
2.	Hyperparathyroidism
3.	Rheumatoid Arthritis

Experts

1.	Futamura, Kenta: 1 article (01/2022)
2.	Goto, Norihiko: 1 article (01/2022)
3.	Hiramitsu, Takahisa: 1 article (01/2022)
4.	Ichimori, Toshihiro: 1 article (01/2022)
5.	Kobayashi, Takaaki: 1 article (01/2022)
6.	Narumi, Shunji: 1 article (01/2022)
7.	Okada, Manabu: 1 article (01/2022)
8.	Sato, Tetsuhiko: 1 article (01/2022)
9.	Tominaga, Yoshihiro: 1 article (01/2022)
10.	Tomosugi, Toshihide: 1 article (01/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hyperparathyroidism 1:

1.	Phosphates (Orthophosphate)IBA 12/01/2003 - "Our goals were to determine whether differences in serum phosphate values at parathyroidectomy (PTX) in hemodialysis patients with refractory hyperparathyroidism: (1) correlated with parathyroid cell proliferation; and (2) affected the antiproliferative response to in vitro calcitriol. "
2.	Parathyroid Hormone (Parathormone)IBA 01/01/2022 - "Normocalcemia was defined as total serum calcium levels of 8.5-10.5 mg/dL, while hyperparathyroidism was defined as when intact parathyroid hormone levels exceeded 80 pg/mL. The patients were divided into two groups based on the presence of hyperparathyroidism 1 year after KTx. "
3.	CalciumIBA 01/01/2022 - "Normocalcemia was defined as total serum calcium levels of 8.5-10.5 mg/dL, while hyperparathyroidism was defined as when intact parathyroid hormone levels exceeded 80 pg/mL. The patients were divided into two groups based on the presence of hyperparathyroidism 1 year after KTx. "
4.	Calcitriol (Calcijex)FDA LinkGeneric 12/01/2003 - "Our goals were to determine whether differences in serum phosphate values at parathyroidectomy (PTX) in hemodialysis patients with refractory hyperparathyroidism: (1) correlated with parathyroid cell proliferation; and (2) affected the antiproliferative response to in vitro calcitriol. "
5.	Adrenal Cortex Hormones (Corticosteroids)IBA 06/01/2003 - "Other risk factors were rheumatoid arthritis (4), osteomalacia (4), corticosteroid treatment (4), and hyperparathyroidism (1). "
6.	Cinacalcet (Sensipar)FDA Link 01/01/2014 - "Individuals in the verum group were more likely to receive cinacalcet therapy (45.5% versus 14.3%, p = 0.0000), and they had higher pill burdens for the treatment of hyperparathyroidism (1.40 ± 0.08 versus 0.72 ± 0.03 pills per patient, p = 0.0000) whilst they were on the waiting list for transplantation. "

Therapies and Procedures

1.	Parathyroidectomy 12/01/2003 - "Our goals were to determine whether differences in serum phosphate values at parathyroidectomy (PTX) in hemodialysis patients with refractory hyperparathyroidism: (1) correlated with parathyroid cell proliferation; and (2) affected the antiproliferative response to in vitro calcitriol. "
2.	Transplantation 01/01/2014 - "Individuals in the verum group were more likely to receive cinacalcet therapy (45.5% versus 14.3%, p = 0.0000), and they had higher pill burdens for the treatment of hyperparathyroidism (1.40 ± 0.08 versus 0.72 ± 0.03 pills per patient, p = 0.0000) whilst they were on the waiting list for transplantation. "
3.	Therapeutics 01/01/2014 - "Individuals in the verum group were more likely to receive cinacalcet therapy (45.5% versus 14.3%, p = 0.0000), and they had higher pill burdens for the treatment of hyperparathyroidism (1.40 ± 0.08 versus 0.72 ± 0.03 pills per patient, p = 0.0000) whilst they were on the waiting list for transplantation. "
4.	Renal Dialysis (Hemodialysis) 12/01/2003 - "Our goals were to determine whether differences in serum phosphate values at parathyroidectomy (PTX) in hemodialysis patients with refractory hyperparathyroidism: (1) correlated with parathyroid cell proliferation; and (2) affected the antiproliferative response to in vitro calcitriol. "