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Myopia 1

Also Known As:

MYP1; Myopia, X-Linked

Networked: 16 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Eye Diseases: 3522
- Refractive Errors: 3499
  - Myopia: 8363
    - Myopia 1: 16
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - X-Linked Genetic Diseases: 42
    - Myopia 1: 16

Related Diseases

1.	Mydriasis
2.	Hyperopia (Hypermetropia)
3.	Pectus Carinatum
4.	Corneal Perforation
5.	Exfoliation Syndrome

Experts

1.	Chen, Ruimin: 1 article (08/2021)
2.	Shangguan, Huakun: 1 article (08/2021)
3.	Xu, Yuanbin: 1 article (08/2021)
4.	Curragh, David: 1 article (03/2020)
5.	Juniat, Valerie: 1 article (03/2020)
6.	McGilligan, J Anthony: 1 article (03/2020)
7.	Rajak, Saul: 1 article (03/2020)
8.	Selva, Dinesh: 1 article (03/2020)
9.	Karabas, V Levent: 1 article (01/2019)
10.	Subasi, Sevgi: 1 article (01/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Myopia 1:

1.	Atropine FDA LinkGeneric 02/01/2012 - "Our previous study, Atropine for the Treatment of Myopia 1 (ATOM1), showed that atropine 1% eyedrops were effective in controlling myopic progression but with visual side effects resulting from cycloplegia and mydriasis. " 06/01/2015 - "Case report of a 39-year-old, otherwise healthy woman who experienced decreased vision, bilateral acute angle closure, choroidal thickening as measured with enhanced depth optical coherence tomography imaging, bilateral suprachoroidal effusions, and induced myopia 1 week after starting a weight loss medication, Qysmia, composed of phentermine 3.75 mg and topiramate 23 mg. Treatment was initiated with high-dose intravenous methylprednisolone, intravenous mannitol, topical difluprednate ophthalmic emulsion, atropine sulfate, and the fixed combination of brimonidine and timolol. "
2.	Ophthalmic Solutions (Eye Drops)IBA 02/01/2012 - "Our previous study, Atropine for the Treatment of Myopia 1 (ATOM1), showed that atropine 1% eyedrops were effective in controlling myopic progression but with visual side effects resulting from cycloplegia and mydriasis. "
3.	Human Growth Hormone (Saizen)FDA LinkGeneric 08/25/2021 - "Among them, 7 patients with height lower than two standard deviations of the mean (or below the third percentile) were treated with recombinant human growth hormone (rhGH), and were followed up every The clinical characteristics were as following: facial anomalies (=12), short stature (=11), congenital heart diseases (=5), facial freckles (=4), coffee spots on the skin (=3), intelligence disability (=3),cryptorchidism (=3), feeding difficulties (=2), scoliosis (=2), pectus carinatum (=2), pectus excavatum (=1), rib dysplasia companied with short finger (=1), hyperopia (=1), myopia (=1) and early puberty (=1). "
4.	Timolol (Blocadren)FDA LinkGeneric 06/01/2015 - "Case report of a 39-year-old, otherwise healthy woman who experienced decreased vision, bilateral acute angle closure, choroidal thickening as measured with enhanced depth optical coherence tomography imaging, bilateral suprachoroidal effusions, and induced myopia 1 week after starting a weight loss medication, Qysmia, composed of phentermine 3.75 mg and topiramate 23 mg. Treatment was initiated with high-dose intravenous methylprednisolone, intravenous mannitol, topical difluprednate ophthalmic emulsion, atropine sulfate, and the fixed combination of brimonidine and timolol. "
5.	Serine (L-Serine)FDA Link 10/01/1995 - "An 1150 amino acid open reading frame is present at the myp1 locus; the predicted polypeptide is rich in serine residues and contains short regions with similarity to SH3 domain ligands. "
6.	Retinaldehyde (Retinal)IBA 11/01/2017 - "This review will revisit several key points of evidence for and against DA mediating light control of myopia: 1) the causal role of extracellular retinal DA levels, 2) the mechanism and action of dopamine D1 and D2 receptors and 3) the roles of cellular/circuit retinal pathways. "
7.	Phentermine (Adipex-P)FDA LinkGeneric 06/01/2015 - "Case report of a 39-year-old, otherwise healthy woman who experienced decreased vision, bilateral acute angle closure, choroidal thickening as measured with enhanced depth optical coherence tomography imaging, bilateral suprachoroidal effusions, and induced myopia 1 week after starting a weight loss medication, Qysmia, composed of phentermine 3.75 mg and topiramate 23 mg. Treatment was initiated with high-dose intravenous methylprednisolone, intravenous mannitol, topical difluprednate ophthalmic emulsion, atropine sulfate, and the fixed combination of brimonidine and timolol. "
8.	Peptides (Polypeptides)IBA 10/01/1995 - "An 1150 amino acid open reading frame is present at the myp1 locus; the predicted polypeptide is rich in serine residues and contains short regions with similarity to SH3 domain ligands. "
9.	Methylprednisolone FDA LinkGeneric 06/01/2015 - "Case report of a 39-year-old, otherwise healthy woman who experienced decreased vision, bilateral acute angle closure, choroidal thickening as measured with enhanced depth optical coherence tomography imaging, bilateral suprachoroidal effusions, and induced myopia 1 week after starting a weight loss medication, Qysmia, composed of phentermine 3.75 mg and topiramate 23 mg. Treatment was initiated with high-dose intravenous methylprednisolone, intravenous mannitol, topical difluprednate ophthalmic emulsion, atropine sulfate, and the fixed combination of brimonidine and timolol. "
10.	Mannitol (Osmitrol)FDA LinkGeneric 06/01/2015 - "Case report of a 39-year-old, otherwise healthy woman who experienced decreased vision, bilateral acute angle closure, choroidal thickening as measured with enhanced depth optical coherence tomography imaging, bilateral suprachoroidal effusions, and induced myopia 1 week after starting a weight loss medication, Qysmia, composed of phentermine 3.75 mg and topiramate 23 mg. Treatment was initiated with high-dose intravenous methylprednisolone, intravenous mannitol, topical difluprednate ophthalmic emulsion, atropine sulfate, and the fixed combination of brimonidine and timolol. "

Therapies and Procedures

1.	Laser In Situ Keratomileusis (LASIK) 03/01/2014 - "The role of the mesopic pupil on patient-reported outcomes in young patients with myopia 1 month after wavefront-guided LASIK." 11/01/2005 - "A 30-year-old man who had laser in situ keratomileusis (LASIK) for myopia 1 year earlier developed a corneal perforation in the left eye from a boa constrictor. "
2.	Phacoemulsification 11/01/2004 - "A 59-year-old woman developed progressive, moderate myopia 1 year after routine phacoemulsification and insertion of a soft posterior chamber intraocular lens (IOL). " 08/01/1992 - "An unusual deepening of the anterior chamber during a phacoemulsification procedure was observed in 3 patients with cataracts: 1 with high myopia, 1 with a lens opacification following a vitrectomy procedure, and 1 with pseudoexfoliation syndrome. "
3.	Vitreoretinal Surgery 01/01/2019 - "The predisposing factors for late in-the-bag spontaneous IOL dislocations were pseudoexfoliation [PEX; 12/39 (30.8%)], previous vitreoretinal surgery [7/39 (17.9%)], axial myopia [3/39 (7.7%)], both PEX and axial myopia [1/39 (2.6%)], both previous vitreoretinal surgery and axial myopia [2/39 (5.1%)] and uveitis [1/39 (2.6%)]. "
4.	Refractive Surgical Procedures 09/15/1993 - "After a long period of hesitation and reluctance, surgery of moderate to mild myopia (1 to 6 dioptries) is currently practiced by specialists in refractive surgery. "
5.	Epikeratophakia 01/01/1989 - "We have studied our results of 15 epikeratophakias for aphakia, 13 for myopia, 1 for a keratoconus and 1 for a bullous keratopathy. "