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Narcolepsy 1
PROM
Also Known As:
NRCLP1; Narcoleptic Syndrome 1
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Disease Context: Research Results
Nervous System Diseases: 14178
Sleep Wake Disorders: 3640
Dyssomnias: 27
Intrinsic Sleep Disorders: 11
Disorders of Excessive Somnolence: 2454
Narcolepsy: 2625
Narcolepsy 1: 1
Mental Disorders: 24177
Sleep Wake Disorders: 3640
Dyssomnias: 27
Intrinsic Sleep Disorders: 11
Disorders of Excessive Somnolence: 2454
Narcolepsy: 2625
Narcolepsy 1: 1
Related Diseases
1.
Narcolepsy
2.
Cataplexy
Drugs and Biologics
Drugs and Important Biological Agents (IBA) related to Narcolepsy 1:
1.
Prazosin (Minipress)
FDA Link
Generic
06/19/1989 - "
Our results of in vivo pharmacology and in vitro [3H]prazosin binding in canine narcolepsy now clearly implicate the low affinity [3H]prazosin binding site (alpha 1b) in canine narcolepsy: (1) Prazosin, an alpha 1 antagonist with similar affinity for both subtypes, was much more potent in increasing cataplexy than WB4101, a compound with more affinity for the alpha 1a receptor.
"
2.
(2- (2',6'- dimethoxy)phenoxyethylamino)methylbenzo- 1,4- dioxane
IBA
06/19/1989 - "
Our results of in vivo pharmacology and in vitro [3H]prazosin binding in canine narcolepsy now clearly implicate the low affinity [3H]prazosin binding site (alpha 1b) in canine narcolepsy: (1) Prazosin, an alpha 1 antagonist with similar affinity for both subtypes, was much more potent in increasing cataplexy than WB4101, a compound with more affinity for the alpha 1a receptor.
"