Methemoglobin Reductase Deficiency

Also Known As:

NADPH-Dependent Methemoglobin Reductase Deficiency; TPNH-Methemoglobin Reductase Deficiency

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Congenital Methemoglobinemia
2.	Methemoglobinemia
3.	Hemolysis
4.	Hemoglobinopathies
5.	Glucosephosphate Dehydrogenase Deficiency

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Methemoglobin Reductase Deficiency:

1.	MethemoglobinIBA 11/01/1994 - "Subsequent analysis revealed 49.6% methemoglobin (normal, 0 to 1.1%), resulting from erythrocyte methemoglobin reductase deficiency (21% of normal activity)." 05/01/1999 - "Among the causes of life-long cyanosis are congenital methemoglobinemia due to M hemoglobins, congenital methemoglobinemia due to methemoglobin reductase deficiency, a small number of low oxygen affinity hemoglobins, and a small number of unstable hemoglobins that spontaneously form methemoglobin in vivo at an accelerated rate. "
2.	Sodium NitriteIBA 10/01/1985 - "Both cytochemical detection of G6PD-deficient cells in a female heterozygote for G6PD deficiency and the screening test for a methemoglobin reductase deficiency could be performed with butylnitrite as well as with sodium nitrite. "
3.	Oxygen (Dioxygen)IBA 05/01/1999 - "Among the causes of life-long cyanosis are congenital methemoglobinemia due to M hemoglobins, congenital methemoglobinemia due to methemoglobin reductase deficiency, a small number of low oxygen affinity hemoglobins, and a small number of unstable hemoglobins that spontaneously form methemoglobin in vivo at an accelerated rate. "
4.	NAD (NADH)IBA 01/01/1972 - "[Congenital methemoglobinemia due to NADH (DPNH) dependent methemoglobin reductase deficiency]."
5.	Hemoglobins (Hemoglobin)IBA 05/01/1999 - "Among the causes of life-long cyanosis are congenital methemoglobinemia due to M hemoglobins, congenital methemoglobinemia due to methemoglobin reductase deficiency, a small number of low oxygen affinity hemoglobins, and a small number of unstable hemoglobins that spontaneously form methemoglobin in vivo at an accelerated rate. "
6.	EnzymesIBA 11/01/1967 - "TPNH-methemoglobin reductase deficiency: a new red-cell enzyme defect."
7.	Dapsone FDA Link 08/01/1981 - "Dapsone-induced methemoglobinemia and hemolysis in the presence of familial hemoglobinopathy Hasharon and familial methemoglobin reductase deficiency."
8.	Ascorbic Acid (Vitamin C)FDA LinkGeneric 10/01/1977 - "In methemoglobinemic conditions caused by toxic effects or by congenital methemoglobin reductase deficiency treatment with ascorbic acid is possible. "