Congenital Preauricular Fistulae

Abnormal congenital passages (fistulae) that usually occur at the upper anterior end of the outer ear helix. OMIM: 128700

Also Known As:

Preauricular Fistulae, Congenital; Ear Pits; PAFC

Networked: 81 relevant articles (3 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Musculoskeletal Diseases: 719
- Musculoskeletal Abnormalities: 43
  - Craniofacial Abnormalities: 203
    - Congenital Preauricular Fistulae: 81
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Musculoskeletal Abnormalities: 43
    - Craniofacial Abnormalities: 203
      - Congenital Preauricular Fistulae: 81

Related Diseases

1.	Leukemia
2.	Circulating Neoplastic Cells
3.	Melanoma (Melanoma, Malignant)
4.	Congenital Diaphragmatic Hernias
5.	Carcinogenesis

Experts

1.	Zharov, Vladimir P: 13 articles (10/2019 - 09/2007)
2.	Sarimollaoglu, Mustafa: 11 articles (10/2019 - 04/2010)
3.	Galanzha, Ekaterina I: 10 articles (10/2019 - 09/2007)
4.	Nedosekin, Dmitry A: 10 articles (11/2018 - 04/2010)
5.	Menyaev, Yulian A: 6 articles (11/2018 - 01/2013)
6.	Jin, Yan: 6 articles (10/2018 - 10/2016)
7.	Li, Hongmin: 6 articles (10/2018 - 10/2016)
8.	Pei, Haiyan: 6 articles (10/2018 - 10/2016)
9.	Sun, Jiongming: 6 articles (10/2018 - 10/2016)
10.	Xu, Hangzhou: 6 articles (10/2018 - 10/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Congenital Preauricular Fistulae:

1.	ferric chlorideIBA 08/01/2000 - "[Study of polyaluminium ferric chloride (PAFC) aqueous solutions visible spectra: the relationship among their absorbance at 460 nm, basicities and total Fe(III) concentration of PAFC solutions]." 03/01/2018 - "The results of compositional analyses suggested that polyaluminum ferric chloride (PAFC) used during the surface water treatment was an important factor in the mineralogy and reactivity of MnOx. " 01/01/2018 - "raciborskii during polyaluminum ferric chloride (PAFC) coagulation and sludge storage, revealing its differences from Microcystis aeruginosa. " 02/01/2002 - "Mid-IR spectra of polyaluminum ferric chloride (PAFC) with different Al/Fe molar ratio were studied by Fourier transform infrared spectroscopy. " 10/01/2018 - "This is the first study to investigate the effect of the conventional coagulant polyaluminium ferric chloride (PAFC) on removal of Oscillatoria sp., and the behavior of Oscillatoria sp. cells in sludges formed from different dosages of PAFC (control, optimum, and overdose system) during storage was also studied. "
2.	CoagulantsIBA 01/01/2017 - "Overall, this study revealed the trends in variation of DW quality for cyanobacteria-containing sludges formed with different coagulants, then FeCl3 and PAFC coagulants are recommended and sludge should be treated or disposed of within 4 days." 10/01/2018 - "This is the first study to investigate the effect of the conventional coagulant polyaluminium ferric chloride (PAFC) on removal of Oscillatoria sp., and the behavior of Oscillatoria sp. cells in sludges formed from different dosages of PAFC (control, optimum, and overdose system) during storage was also studied. " 11/15/2015 - "In this study, an inorganic composite coagulant, polyaluminum ferric chloride (PAFC), was prepared and used in surface water treatment, and the influence of Al/Fe molar ratio and basicity (B) on floc properties was investigated. " 09/16/2021 - "A relatively better removal performance (<99%) of CuO NPs was found at lower coagulant dosage in the pH range 6-8. The addition of organic ligands reversed the surface charge potential and enhanced the colloidal stability of CuO NPs, resulting in the destabilization of TA-CuO NPs, thereby reducing the optimum PAFC dosage for removal. " 01/01/2003 - "Evaluation of polyaluminium ferric chloride (PAFC) as a composite coagulant for water and wastewater treatment."
3.	Coloring Agents (Dyes)IBA 01/01/2015 - "Decolorization efficiency using PAFC-EPI-ETA was quite effecient with pH range of 6.0-7.5 for RBR dye removal. " 10/01/2011 - "We further analyze the potential of integrated PAFC/PT spectroscopy with multiple dyes for rapid and accurate measurements of circulating blood volume without a priori information on hemoglobin content, which is impossible with existing optical techniques. " 10/01/2011 - "Here, we propose multispectral PAFC with multiple dyes having distinctive absorption spectra as multicolor PA contrast agents. " 01/01/2003 - "PAFC gives good color removal performance on suspension dyes. " 10/01/2011 - "The possibility for accurate measurements of various dye concentrations including Crystal Violet and Brilliant Green were verified in vitro using complementary to PAFC photothermal (PT) technique and spectrophotometry under batch and flow conditions. "
4.	Tannic Acid FDA Link 09/16/2021 - "Removal of Tannic Acid Stabilizes CuO Nanoparticles from Aqueous Media by PAFC: Effect of Process Conditions and Water Chemistry." 09/16/2021 - "The present study explored the efficacy of the coagulation-sedimentation (C/S) process for the removal of tannic acid (TA)-stabilized CuO NPs using polyaluminum ferric chloride (PAFC) as a coagulant. "
5.	Biomarkers (Surrogate Marker)IBA 04/12/2010 - "In vivo photoacoustic (PA) flow cytometry (PAFC) has great potential for detecting disease-associated biomarkers in blood and lymph flow, as well as real-time control of the efficacy of photothermal (PT) and other therapies through the counting of circulating abnormal objects. "
6.	Trypan Blue FDA Link 10/01/2011 - "As a first step of our proof-of-concept, we characterized high-speed PAFC capability to monitor the clearance of three dyes (Indocyanine Green [ICG], Methylene Blue [MB], and Trypan Blue [TB]) in an animal model in vivo and in real time. "
7.	Methylene Blue (Methylthioninium Chloride)FDA Link 10/01/2011 - "As a first step of our proof-of-concept, we characterized high-speed PAFC capability to monitor the clearance of three dyes (Indocyanine Green [ICG], Methylene Blue [MB], and Trypan Blue [TB]) in an animal model in vivo and in real time. "
8.	Indocyanine Green (Cardio-Green)FDA LinkGeneric 10/01/2011 - "As a first step of our proof-of-concept, we characterized high-speed PAFC capability to monitor the clearance of three dyes (Indocyanine Green [ICG], Methylene Blue [MB], and Trypan Blue [TB]) in an animal model in vivo and in real time. "
9.	Aluminum ChlorideIBA 11/07/2017 - "Results show that Cyanobacteria, Proteobacteria, Firmicutes, Bacteroidetes, Verrucomicrobia, and Planctomycetes were the most dominant phyla in sludge, and because of the toxicity of high Al and Fe level in AlCl3 and FeCl3 sludges, respectively, the PAFC sludge exhibited greater microbial richness than that in AlCl3 and FeCl3 sludges. " 10/07/2016 - "Although the cell viability in FeCl3 sludge was low (similar to AlCl3 sludge), the Microcystis aeruginosa cells remained basically intact after 10 d storage (similar to PAFC sludge). " 10/07/2016 - "The lysis of Microcystis aeruginosa in AlCl3 sludge was more serious than that in PAFC sludge, for the same storage time. " 10/07/2016 - "In AlCl3 and FeCl3 sludges high concentrations of Al and Fe were toxic to Microcystis aeruginosa, whereas in PAFC sludge low levels of Al showed little toxic effect on Microcystis aeruginosa growth and moderate amounts of Fe were beneficial to growth. " 10/07/2016 - "Results show that the viability of Microcystis aeruginosa in PAFC sludge was stronger than that of cells in either AlCl3 or FeCl3 sludge after the same storage time, while the cells' viability in the latter two systems stayed at almost the same level. "
10.	AluminumIBA 03/18/2022 - "It demonstrates that extracting aluminum and iron ions from high iron content gangue to prepare PAFC by microwave is efficient and feasible." 03/18/2022 - "Poly aluminum-ferric Chloride (PAFC) is a new type of high efficiency coagulant. " 05/15/2017 - "The flocculation efficiency of CS-g-P(AM-DMDAAC) were significantly higher than those obtained by cationic polyacrylamide (CPAM) and Polymeric aluminum and iron (PAFC). " 01/01/2010 - "The average concentrations of polynuclear aluminum (Al(b)) and colloidal/suspended aluminum (Al(c)) in the drinking water treated by alum were lower than those in water treated by PACl and PAFC. " 10/07/2016 - "This is the first study to systematically investigate the different behaviors of Microcystis aeruginosa in the sludges formed by AlCl3, FeCl3, and polymeric aluminium ferric chloride (PAFC) coagulants during storage. "

Therapies and Procedures

1.	Therapeutics 08/19/2020 - "The lack of hemolytic activity further corroborates the potential applicability of PAFC in clinical therapy." 08/19/2020 - "The functional characterization of recombinant PAFC provided evidence for a promising new molecule in anti-Candida therapy. " 01/01/2016 - "A combination of linear and nonlinear nanobubble-based multicolor PAFC showed capability to real-time control therapy efficiency by counting of iRBCs before, during, and after treatment. " 01/01/2016 - "The insight on embolus dynamics during cancer progression and medical procedures highlight the clinical potential of PAFC for early detection of cancer and surgery-induced emboli to prevent the fatal thromboembolic complications by well-timed therapy. " 04/12/2010 - "In vivo photoacoustic (PA) flow cytometry (PAFC) has great potential for detecting disease-associated biomarkers in blood and lymph flow, as well as real-time control of the efficacy of photothermal (PT) and other therapies through the counting of circulating abnormal objects. "
2.	Lasers (Laser) 11/01/2018 - "In the current study, we extend applicability of PAFC for detection of CBCs in relatively large (1.5-2 mm) and deep (up to 5-6 mm) blood vessels in rat and rabbit models using a high pulse rate 1064 nm laser and focused ultrasound transducer with a central hole for an optic fiber. " 11/01/2019 - "PAFC is the generation of ultrasonic waves created by the absorption of laser light in particles under flow. " 11/01/2017 - "In this work, we present a laser-based optical detection methodology for noninvasive detection and pharmacokinetics analysis of GBNs directly in blood flow in mice using in vivo photoacoustic (PA) flow cytometry (PAFC). " 01/01/2016 - "Multicolor time-of-flight PAFC with high-pulse repetition rate lasers at wavelengths of 532, 671, and 820 nm demonstrated rapid spectral and spatial identification and quantitative enumeration of individual iRBCs. " 10/01/2011 - "Demonstrated label-free PAFC detection, low level of background signals, and favorable safety standards for near-infrared irradiation suggest that a fiber laser operating at 1064 nm at pulse repetition rates up to 0.5 MHz could be a promising source for portable clinical PAFC devices. "
3.	Catheters 01/01/2023 - "Therefore, the purpose of this study was to investigate the changes in the left and right heart function during the PCRTO process combined with a pulmonary artery flotation catheter (PAFC). " 01/01/2023 - "Pulmonary artery flotation catheter (PAFC) combined with pump-controlled retrograde trial off (PCRTO) as a trial for weaning VA-ECMO patients: A retrospective study." 06/01/2003 - "In some patients passage of a pulmonary artery flotation catheter (PAFC) into the pulmonary artery may be difficult and time consuming and the prolonged manipulation can cause ventricular arrhythmias. " 01/01/1984 - "We found a significant platelet decrease in the PAFC group at 6 h (p less than 0.001), 24 h (p less than 0.001), 48 h (p less than 0.001) and 72 h (p less than 0.001) after catheter placement, compared to the control group. " 11/01/2018 - "We confirmed that PAFC can detect both red and white CBCs induced by microsurgical procedures, such as a needle or catheter insertion, as well as stroke modeled by injection of artificial clots. "
4.	Precision Medicine 10/02/2019 - "The integration of in vitro and in vivo methods, PAFC-guided theranostics of single CTCs and targeted drug delivery are discussed as future perspectives."
5.	Semiconductor Lasers 10/01/2018 - "Using a laser diode, we demonstrated the extraordinary ability of PAFC to dynamically detect fast-moving mimic CTCs with positive PA contrast and white clots with negative PA contrast in an RBC background. "