Thyroid Dyshormonogenesis 4

Also Known As:

Deiodinase Deficiency; Hypothyroidism, Congenital, due to Dyshormonogenesis, 4; Iodotyrosine Dehalogenase Deficiency; Thyroid Hormonogenesis, Genetic Defect in, 4

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Hypothyroidism
2.	Goiter

Experts

1.	Beber, Eduardo H: 1 article (01/2019)
2.	Capelo, Luciane P: 1 article (01/2019)
3.	Dora, José M: 1 article (01/2019)
4.	Fonseca, Tatiana L: 1 article (01/2019)
5.	Freitas, Fatima R: 1 article (01/2019)
6.	Gouveia, Cecilia H A: 1 article (01/2019)
7.	Maia, Ana L: 1 article (01/2019)
8.	Miranda-Rodrigues, Manuela: 1 article (01/2019)
9.	Nonaka, Keico O: 1 article (01/2019)
10.	Wang, Charles C: 1 article (01/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Thyroid Dyshormonogenesis 4:

1.	Thyroid HormonesIBA 01/01/2019 - "Abnormal Thyroid Hormone Status Differentially Affects Bone Mass Accrual and Bone Strength in C3H/HeJ Mice: A Mouse Model of Type I Deiodinase Deficiency." 11/01/2010 - "Type 3 deiodinase deficiency causes spatial and temporal alterations in brain T3 signaling that are dissociated from serum thyroid hormone levels." 06/01/2013 - "These genes are potential biomarkers for detecting deiodinase deficiency and predicting their effects on thyroid hormone production."
2.	IodineIBA 06/01/1986 - "Deiodinase deficiency was diagnosed by a rapid thyroid uptake of radioactive iodine (RAI) at 2 hours associated with a marked fall in thyroidal 131I by 24 hours. " 12/01/2008 - "The recent cloning of the human iodotyrosine deiodinase (IYD) gene enables the investigation of iodotyrosine dehalogenase deficiency, a form a primary hypothyroidism resulting from iodine wasting, at the molecular level. "
3.	Biomarkers (Surrogate Marker)IBA 06/01/2013 - "These genes are potential biomarkers for detecting deiodinase deficiency and predicting their effects on thyroid hormone production."
4.	Thyroxine (Levothyroxine)FDA LinkGeneric 03/01/1977 - "Three siblings (products of consanguineous marriage) affected with iodotyrosine-dehalogenase deficiency (presumed homozygotes) were found to have low thyroxine and large multinodular goiters, but none was mentally retarded. "
5.	Iodide Peroxidase (Deiodinase)IBA 12/01/2008 - "The recent cloning of the human iodotyrosine deiodinase (IYD) gene enables the investigation of iodotyrosine dehalogenase deficiency, a form a primary hypothyroidism resulting from iodine wasting, at the molecular level. "
6.	EnzymesIBA 05/01/2011 - "Given the increasing availability of genetic models of deiodinase deficiency, new insights into the role of these important enzymes are being recognized. "
7.	DiiodotyrosineIBA 01/01/1978 - "The test of overloading L-diiodotyrosine (DIT) in the screening of iodotyrosine dehalogenase deficiency."