2 Age-Related Macular Degeneration

A hereditary form of macular degeneration that occurs in elderly individuals. It is associated with mutations in the ABCA4 gene. OMIM: 153800

Also Known As:

Macular Degeneration, Age-Related, 2; Armd2; Macular Degeneration, Senile; Maculopathy, Age-Related, 2

Networked: 5 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Eye Diseases: 3522
- Retinal Diseases: 3014
  - Retinal Degeneration: 4078
    - Macular Degeneration: 15480
      - 2 Age-Related Macular Degeneration: 5

Related Diseases

1.	Macular Degeneration (Age-Related Maculopathy)
2.	Histoplasmosis
3.	Proliferative Vitreoretinopathy
4.	Telangiectasis (Telangiectasia)
5.	Retinal Vein Occlusion

Experts

1.	Kobat, Sabiha Gungor: 1 article (01/2020)
2.	Turgut, Burak: 1 article (01/2020)
3.	Agarwal, Anita: 1 article (01/2007)
4.	Caldwell, Jennifer: 1 article (01/2007)
5.	Gallins, Paul: 1 article (01/2007)
6.	Haines, Jonathan L: 1 article (01/2007)
7.	Hauser, Michael A: 1 article (01/2007)
8.	Pericak-Vance, Margaret A: 1 article (01/2007)
9.	Postel, Eric A: 1 article (01/2007)
10.	Schmidt, Silke: 1 article (01/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to 2 Age-Related Macular Degeneration:

1.	ArgonIBA 04/01/1986 - "Results from the Macular Photocoagulation Study Group have shown that argon laser photocoagulation is beneficial in reducing the risk of severe visual loss in eyes with extrafoveal choroidal neovascular membranes secondary to senile macular degeneration (Senile Macular Degeneration Study or SMDS), ocular histoplasmosis (Ocular Histoplasmosis Study or OHS), or idiopathic neovascularization (Idiopathic Neovascularization Study or INVS). " 05/01/1986 - "The Macular Photocoagulation Study randomized controlled clinical trials designed to determine whether argon laser photocoagulation is effective for preventing or delaying severe visual loss in eyes with an extrafoveal choroidal neovascular membrane secondary to senile macular degeneration (Senile Macular Degeneration Study [SMDS]), ocular histoplasmosis (Ocular Histoplasmosis Study [OHS]), or idiopathic neovascularization (Idiopathic Neovascularization Study [INVS]). "
2.	Complement Factor H (Factor H)IBA 01/01/2007 - "To compare phenotypes of 2 age-related macular degeneration (AMD) susceptibility genes: LOC387715 and complement factor H (CFH). "
3.	Methanol (Carbinol)IBA 01/01/2020 - "Additionally, there has been consideration that MC dysfunction might contribute to the pathogenesis of some retinal diseases, such as proliferative vitreoretinopathy, diabetic retinopathy, macular edema, retinal vein occlusion, macular telangiectasia type 2, age-related macular degeneration, retinal degeneration, hepatic and methanol-induced retinopathy, and glaucoma. "

Therapies and Procedures

1.	Light Coagulation 04/01/1986 - "Results from the Macular Photocoagulation Study Group have shown that argon laser photocoagulation is beneficial in reducing the risk of severe visual loss in eyes with extrafoveal choroidal neovascular membranes secondary to senile macular degeneration (Senile Macular Degeneration Study or SMDS), ocular histoplasmosis (Ocular Histoplasmosis Study or OHS), or idiopathic neovascularization (Idiopathic Neovascularization Study or INVS). " 05/01/1986 - "The Macular Photocoagulation Study randomized controlled clinical trials designed to determine whether argon laser photocoagulation is effective for preventing or delaying severe visual loss in eyes with an extrafoveal choroidal neovascular membrane secondary to senile macular degeneration (Senile Macular Degeneration Study [SMDS]), ocular histoplasmosis (Ocular Histoplasmosis Study [OHS]), or idiopathic neovascularization (Idiopathic Neovascularization Study [INVS]). "
2.	Lasers (Laser) 04/01/1986 - "Results from the Macular Photocoagulation Study Group have shown that argon laser photocoagulation is beneficial in reducing the risk of severe visual loss in eyes with extrafoveal choroidal neovascular membranes secondary to senile macular degeneration (Senile Macular Degeneration Study or SMDS), ocular histoplasmosis (Ocular Histoplasmosis Study or OHS), or idiopathic neovascularization (Idiopathic Neovascularization Study or INVS). " 05/01/1986 - "The Macular Photocoagulation Study randomized controlled clinical trials designed to determine whether argon laser photocoagulation is effective for preventing or delaying severe visual loss in eyes with an extrafoveal choroidal neovascular membrane secondary to senile macular degeneration (Senile Macular Degeneration Study [SMDS]), ocular histoplasmosis (Ocular Histoplasmosis Study [OHS]), or idiopathic neovascularization (Idiopathic Neovascularization Study [INVS]). "
3.	Drug Therapy (Chemotherapy) 12/12/2022 - "Previous medical history included diabetes mellitus (n = 2), age-related macular degeneration (n = 1), and Multiple myeloma under chemotherapy (n = 1). "