X-Linked Hypogammaglobulinemia

mutation in Bruton tyrosine kinase

Also Known As:

Hypogammaglobulinemia, X-Linked

Networked: 13 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Hemic and Lymphatic Diseases: 6
- Hematologic Diseases: 3366
  - Blood Protein Disorders: 17
    - Agammaglobulinemia: 1550
      - X-Linked Hypogammaglobulinemia: 13
- Lymphatic Diseases: 92
  - Lymphoproliferative Disorders: 4250
    - Agammaglobulinemia: 1550
      - X-Linked Hypogammaglobulinemia: 13
Immune System Diseases: 4321
- Immunologic Deficiency Syndromes: 91
  - Agammaglobulinemia: 1550
    - X-Linked Hypogammaglobulinemia: 13
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - X-Linked Genetic Diseases: 42
    - X-Linked Hypogammaglobulinemia: 13

Related Diseases

1.	Encephalitis (Encephalitis, Rasmussen)
2.	Type 1 Hyper-IgM Immunodeficiency Syndrome
3.	Hyper-IgM Immunodeficiency Syndrome (Hyper-IgM Syndrome)
4.	Abdominal Abscess
5.	Polymyositis

Experts

1.	Droitcourt, C: 1 article (06/2016)
2.	Dupuy, A: 1 article (06/2016)
3.	Le Gallou, T: 1 article (06/2016)
4.	Perlat, A: 1 article (06/2016)
5.	Poirot, M: 1 article (06/2016)
6.	Poizeau, F: 1 article (06/2016)
7.	Saillard, C: 1 article (06/2016)
8.	Kobayashi, Masao: 1 article (05/2006)
9.	Miyagawa, Shin-ichiro: 1 article (05/2006)
10.	Nishi, Yoshikazu: 1 article (05/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to X-Linked Hypogammaglobulinemia:

1.	Intravenous Immunoglobulins (IVIG)FDA Link 01/01/1987 - "Intravenous immunoglobulin therapy of progressive encephalitis in X-linked hypogammaglobulinemia." 06/01/2016 - "The present case describes a 19-year-old male with X-linked hypogammaglobulinemia, or Bruton agammaglobulinemia, treated with intravenous immunoglobulin G antibodies. "
2.	Growth Hormone (Somatotropin)IBA 05/28/2006 - "[X-linked hypogammaglobulinemia with growth hormone deficiency]." 01/01/2000 - "[X-linked hypogammaglobulinemia with growth hormone deficiency]."
3.	Agammaglobulinaemia Tyrosine KinaseIBA 12/01/2005 - "X-linked hypogammaglobulinemia with isolated growth hormone deficiency is not caused by Bruton's tyrosine kinase mutations in the family described originally, but may be due to a mutation in myeloid elf-1-like factor." 09/01/1993 - "EMT is related to the B-cell progenitor kinase (BPK), which has recently been implicated in X-linked hypogammaglobulinemia, to the TECI mammalian kinase, which has been implicated in liver neoplasia, to the more widely expressed TECII mammalian kinase, and to the Drosophila melanogaster Dsrc28 kinase. "
4.	CD40 Ligand (CD40L)IBA 01/01/1996 - "Mutation analysis in CD40 ligand deficiency leading to X-linked hypogammaglobulinemia with hyper IgM syndrome." 01/01/1996 - "Mutations in the gene encoding CD40 ligand have been shown to be the cause of X-linked hypogammaglobulinemia with hyper IgM (HIGM1). "
5.	16S Ribosomal RNAIBA 07/01/2000 - "A unique Helicobacter species, MZ640285, was isolated from a patient with X-linked hypogammaglobulinemia suffering from recurrent abdominal abscesses and was identified by 16S rRNA gene sequence analysis. " 07/01/2000 - "Identification of a unique Helicobacter species by 16S rRNA gene analysis in an abdominal abscess from a patient with X-linked hypogammaglobulinemia."
6.	Prednisone (Sone)FDA LinkGeneric 07/01/1986 - "A 29-year-old man with X-linked hypogammaglobulinemia was treated with prednisone and methotrexate for polymyositis. "
7.	Phosphotransferases (Kinase)IBA 09/01/1993 - "EMT is related to the B-cell progenitor kinase (BPK), which has recently been implicated in X-linked hypogammaglobulinemia, to the TECI mammalian kinase, which has been implicated in liver neoplasia, to the more widely expressed TECII mammalian kinase, and to the Drosophila melanogaster Dsrc28 kinase. "
8.	Methotrexate (Mexate)FDA LinkGeneric 07/01/1986 - "A 29-year-old man with X-linked hypogammaglobulinemia was treated with prednisone and methotrexate for polymyositis. "
9.	Immunoglobulins (Immunoglobulin)IBA 02/07/1985 - "Successful reversal of echovirus encephalitis in X-linked hypogammaglobulinemia by intraventricular administration of immunoglobulin."
10.	Immunoglobulin M (IgM)IBA 01/01/1996 - "Mutations in the gene encoding CD40 ligand have been shown to be the cause of X-linked hypogammaglobulinemia with hyper IgM (HIGM1). "

Therapies and Procedures

1.	Therapeutics 08/01/1985 - "A patient with Bruton's X-linked hypogammaglobulinemia, who developed the typical syndrome associated with systemic echovirus 3 infection whilst on routine intramuscular gammaglobulin replacement therapy, is described. " 01/01/1987 - "Intravenous immunoglobulin therapy of progressive encephalitis in X-linked hypogammaglobulinemia."