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2- (2- (3,3- dimethylbutanamido)- 3- methylpentanoyl)- 7- (2- (hydroxyamino)- 2- oxoethoxy)- N- (4- methoxyphenyl)- 1,2,3,4- tetrahydroisoquinoline- 3- carboxamide

has antineoplastic activity; structure in first source

Also Known As:

ZYJ 34c; ZYJ-34c; ZYJ34c

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Hydroxamic Acids: 239
      - 2-(2-(3,3-dimethylbutanamido)-3-methylpentanoyl)-7-(2-(hydroxyamino)-2-oxoethoxy)-N-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide: 1
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Hydroxamic Acids: 239
      - 2-(2-(3,3-dimethylbutanamido)-3-methylpentanoyl)-7-(2-(hydroxyamino)-2-oxoethoxy)-N-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - 2-(2-(3,3-dimethylbutanamido)-3-methylpentanoyl)-7-(2-(hydroxyamino)-2-oxoethoxy)-N-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide: 1

Experts

1.	Lan, Peixiang: 1 article (08/2014)
2.	Li, Yan: 1 article (08/2014)
3.	Xu, Wenfang: 1 article (08/2014)
4.	Yang, Hua: 1 article (08/2014)
5.	Zhang, Cai: 1 article (08/2014)
6.	Zhang, Jian: 1 article (08/2014)
7.	Zhang, Yingjie: 1 article (08/2014)

Related Diseases

1.	Leukemia 08/01/2014 - "ZYJ-34c could represent a novel pharmacological agent with potential benefit for patients with leukemia. " 08/01/2014 - "ZYJ-34c strongly inhibited the proliferation of leukemia cells compared with suberoylanilide hydroxamic acid. "
2.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 08/01/2014 - "Primary leukemic cells isolated from patients with acute myeloid leukemia were more sensitive to ZYJ-34c. "

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