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3- (1- (1- ((4- chlorophenyl)(3- (5- oxo- 4,5- dihydro- 1,3,4- oxadiazol- 2- yl)phenyl)methyl)azetidin- 3- yl)- 2- fluoro- 2- methylpropyl)- 5- fluorobenzonitrile

a CB1 receptor inverse agonist; structure in first source

Also Known As:

MK 7128; MK-7128; MK7128

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - Oxadiazoles: 146
        3-(1-(1-((4-chlorophenyl)(3-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)phenyl)methyl)azetidin-3-yl)-2-fluoro-2-methylpropyl)-5-fluorobenzonitrile: 1
  - Azetines
    - Azetidines: 6
      - 3-(1-(1-((4-chlorophenyl)(3-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)phenyl)methyl)azetidin-3-yl)-2-fluoro-2-methylpropyl)-5-fluorobenzonitrile: 1

Experts

1.	Dillon, Gregory M: 1 article (04/2011)
2.	Dodart, Jean-Cosme: 1 article (04/2011)
3.	Ferguson, Mitchell T: 1 article (04/2011)
4.	Fong, Tung M: 1 article (04/2011)
5.	Hale, Jeffrey J: 1 article (04/2011)
6.	Huang, Ruey-Ruey C: 1 article (04/2011)
7.	Kornecook, Thomas J: 1 article (04/2011)
8.	Lao, Julie Z: 1 article (04/2011)
9.	Lubbers, Laura S: 1 article (04/2011)
10.	Miao, Shouwu: 1 article (04/2011)

Related Diseases

1.

Memory Disorders (Memory Loss)

04/01/2011 - "In this study, we investigated whether MK-7128 (0.1, 0.3, and 1 mg/kg, orally), a novel and selective CB1R inverse agonist, could improve learning and memory deficits induced by scopolamine (1 mg/kg, subcutaneously) in mice. "
04/01/2011 - "MK-7128, a novel CB1 receptor inverse agonist, improves scopolamine-induced learning and memory deficits in mice."

Related Drugs and Biologics

1.	Scopolamine (Hyoscine)
2.	CB1 Cannabinoid Receptor (CB1 Receptor)