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argiotoxin-636

from the venom of Argiope aurantia; blocks neuromuscular transmission in insects; structure in first source.

Also Known As:

AR-636; AR636; ArgTX-636; argiotoxin 636; argiotoxin636

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indoleacetic Acids: 615
        argiotoxin-636: 2
- Heterocyclic Acids
  - Indoleacetic Acids: 615
    - argiotoxin-636: 2
Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - argiotoxin-636: 2

Experts

1.	Bengeloune, Abd Haq: 1 article (11/2016)
2.	Bertin, Denis: 1 article (11/2016)
3.	De Pomyers, Harold: 1 article (11/2016)
4.	Gigmes, Didier: 1 article (11/2016)
5.	Luis, José: 1 article (11/2016)
6.	Mabrouk, Kamel: 1 article (11/2016)
7.	Roudaut, Hermine: 1 article (11/2016)
8.	Verdoni, Marion: 1 article (11/2016)

Related Diseases

1.	Skin Diseases (Skin Disease) 11/15/2016 - "Thus, ArgTX-636 could have particular interest for cosmetic and/or pharmaceutical use in order to reduce important dermatoses in black and mixed skins."
2.	Muscle Hypotonia (Hypotonia) 09/01/1992 - "AR636 was found to evoke a dose-dependent incidence of muscle flaccidity as well as a blockade of the agitation otherwise evoked by noxious mechanical and thermal stimuli applied to the tail or hind paws. "
3.	Melanoma (Melanoma, Malignant) 11/15/2016 - "ArgTX-636 has no cytotoxicity in B16F10 melanoma cells at concentrations up to 42.1μM. " 11/15/2016 - "The effect of ArgTX-636 on melanogenesis showed that melanin production in B16F10 melanoma cell decreased by approximatively 70% compared to untreated cells. "

Related Drugs and Biologics

1.	Melanins (Melanin)