(((5- (1,1- dimethylethyl)thiazol- 2- yl)methyl)(((4- (4- (4- (1- propylbutyl)phenoxy)methyl)phenyl)thiazol- 2- yl)methyl)amino)acetic acid

a hypoglycemic agent and PTP1B inhibitor; structure in first source

Also Known As:

JTT 551; JTT-551; JTT551; monosodium (((5-(1,1-dimethylethyl)thiazol-2-yl)methyl)(((4-(4-(4-(1-propylbutyl)phenoxy)methyl)phenyl)thiazol-2-yl)methyl)amino)acetate

Networked: 2 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Fukuda, Sumiaki: 1 article (01/2014)
2.	Ito, Makoto: 1 article (01/2014)
3.	Morinaga, Hisayo: 1 article (01/2014)
4.	Ohta, Takeshi: 1 article (01/2014)
5.	Sakata, Shohei: 1 article (01/2014)
6.	Fukuda, S: 1 article (04/2010)
7.	Ito, M: 1 article (04/2010)
8.	Matsushita, M: 1 article (04/2010)
9.	Morinaga, H: 1 article (04/2010)
10.	Nakagawa, Y: 1 article (04/2010)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 01/01/2014 - "JTT-551 shows an antiobesity effect possibly by enhancement of leptin signaling and could be useful in the treatment of type 2 diabetes and obesity. " 04/01/2010 - "JTT-551, a newly developed PTP1B inhibitor, improves glucose metabolism by enhancement of insulin signalling and could be useful in the treatment of type 2 diabetes mellitus."
2.	Obesity 01/01/2014 - "We have evaluated an antiobesity effect of JTT-551 using diet-induced obesity (DIO) mice. " 01/01/2014 - "Pharmacological effects of JTT-551, a novel protein tyrosine phosphatase 1B inhibitor, in diet-induced obesity mice." 01/01/2014 - "JTT-551 shows an antiobesity effect possibly by enhancement of leptin signaling and could be useful in the treatment of type 2 diabetes and obesity. "

Related Drugs and Biologics

1.	Leptin
2.	Insulin (Novolin)
3.	Glucose (Dextrose)
4.	Non-Receptor Type 1 Protein Tyrosine Phosphatase