ulipristal acetate

09/01/2018 - "Fibroid treatment with ulipristal acetate resulted in a significant improvement of fibroid-related symptoms; moreover, it proved to be effective in decreasing both uterine and fibroid volumes and fibroid vascularization. "
08/01/2014 - "Recent reports concerning administration of SPRMs, specifically the efficacy of ulipristal acetate in reducing fibroid size and rapid control of menstrual blood loss, have renewed clinical interest in this class of compound. "
05/28/2012 - "A significantly greater median reduction from baseline in total fibroid volume was observed for recipients of ulipristal acetate 5 mg once daily than recipients of placebo following 13 weeks' treatment (coprimary endpoint). "
01/01/2021 - "Ulipristal acetate (UPA) is effective in the treatment of uterine fibroids. "
10/01/2017 - "Ulipristal acetate is an effective and generally well tolerated treatment for patients with symptomatic uterine fibroids, both as preoperative, single-course treatment and as intermittent, longer-term treatment. "

01/01/2022 - "LNG IUD Ulipristal acetate may increase the percentage of bleeding days compared to placebo (MD 9.50, 95% CI 1.48 to 17.52; 1 trial, 118 women; low-certainty evidence). "
01/01/2022 - "LNG IUD The use of ulipristal acetate in LNG IUD may not reduce the number of bleeding days in 90 days in comparison to placebo (MD -9.30 days, 95% CI -26.76 to 8.16; 1 trial, 24 women; low-certainty evidence). "
10/01/2018 - "At the conclusion of the 30-day follow-up period, women in the ulipristal acetate group were more satisfied with their bleeding profile than the placebo group (87.5% vs 60%, respectively; P<.001). "
10/01/2018 - "Secondary outcomes included participant satisfaction with bleeding and the effect of ulipristal acetate on ovulation status. "
10/01/2018 - "Participants completed daily bleeding diaries using automated text messaging to evaluate whether ulipristal acetate reduces the number of bleeding days as compared with placebo. "

05/28/2012 - "Uterine bleeding was rapidly controlled by ulipristal acetate. "
02/02/2012 - "At 13 weeks, uterine bleeding was controlled in 91% of the women receiving 5 mg of ulipristal acetate, 92% of those receiving 10 mg of ulipristal acetate, and 19% of those receiving placebo (P<0.001 for the comparison of each dose of ulipristal acetate with placebo). "
09/01/2013 - "Superior efficacy of ulipristal acetate versus placebo, to reduce excessive uterine bleeding and to reduce total fibroid volume prior to surgery was demonstrated. "
06/01/2023 - "A short course of Ulipristal acetate as promising treatment for acute uterine bleeding without fibroids."
07/01/2018 - "This report suggests that ulipristal acetate could be useful in the treatment of acute uterine bleeding even in a structurally normal uterus without fibroids."

09/01/2014 - "On the other hand, recent studies have demonstrated the efficacy of ulipristal acetate in the medical management of myomas. "
07/01/2020 - "Efficacy of ulipristal acetate (UPA) for the treatment of expulsion uterine myomas: report of two cases."
02/01/2020 - "The clinical question in "PICO" format was in patients affected by uterine myomas undergoing operative hysteroscopic management, "Does UPA impact the surgical outcomes?" We performed a systematic literature search in PubMed/MEDLINE and Embase for original studies written in English (registered in PROSPERO CRD42018092201), using the terms "hysteroscopy" AND "ulipristal acetate" published up to March 2019. "
08/01/2015 - "To study the in vivo mechanisms of action of ulipristal acetate (UPA) on uterine myomas. "
03/01/2022 - "Hysteroscopic and ultrasonographic evaluation of ulipristal acetate treatment for symptomatic myomas in premenopausal women: a prospective study."

01/01/2021 - "Ulipristal acetate versus conventional management of heavy menstrual bleeding (UCON) trial (EudraCT 2014-003408-65; REC14/LO/1602)."
11/01/2021 - "Efficacy of ulipristal acetate in women with fibroid induced menorrhagia: A systematic review and meta-analysis."
09/01/2019 - "Repeated two cycles of ulipristal acetate treatment improve the quality of life in premenopausal women with heavy menstrual bleeding dependent on uterine myomas, without impairment of bone health."
07/01/2018 - "Ulipristal acetate for the management of acute heavy menstrual bleeding without fibroids."
01/01/2017 - "The patient presented with uterine fibroids and heavy menstrual bleeding, and was treated with ulipristal acetate over three 90-day courses. "