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5- hydroxy- 6,7,8,3',4'- pentamethoxyflavone

an antineoplastic agent; structure in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        5-hydroxy-6,7,8,3',4'-pentamethoxyflavone: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        5-hydroxy-6,7,8,3',4'-pentamethoxyflavone: 4

Experts

1.	Li, Shiming: 4 articles (01/2021 - 07/2010)
2.	Ho, Chi-Tang: 3 articles (08/2018 - 07/2010)
3.	Yang, Guliang: 2 articles (01/2021 - 08/2018)
4.	Dong, Ping: 2 articles (04/2011 - 07/2010)
5.	Guan, Huashi: 2 articles (04/2011 - 07/2010)
6.	McClements, David Julian: 2 articles (04/2011 - 07/2010)
7.	Pan, Min-Hsiung: 2 articles (04/2011 - 07/2010)
8.	Qiu, Peiju: 2 articles (04/2011 - 07/2010)
9.	Xiao, Hang: 2 articles (04/2011 - 07/2010)
10.	Shen, Junfeng: 1 article (01/2021)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 04/01/2011 - "Previously, we reported that 5-hydroxy polymethoxyflavones (5OH-PMFs) isolated from orange, namely 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone, 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone (5HHMF) and 5-hydroxy-6,7,8,4'-tetramethoxyflavone (5HTMF), potently induced apoptosis and cell-cycle arrest in multiple human colon cancer cells. " 07/01/2010 - "We studied the effects of three major 5-hydroxy PMFs, namely: 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone, 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone, and 5-hydroxy-6,7,8,4'-tetramethoxyflavone, on human colon cancer HCT116 and HT29 cells. "
2.	Psoriasis (Pustulosis Palmaris et Plantaris) 08/08/2018 - "Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by Regulating the Expression of Ki-67 and Proliferating Cell Nuclear Antigen and the Differentiation of CD4+ T Cells through Mitogen-Activated Protein Kinase Signaling Pathways."
3.	Inflammation (Inflammations) 08/08/2018 - "Flavonoids in chenpi (aged tangerine peel) from tangerine ( Citrus reticulate Blanco), such as nobiletin (Nob), tangeretin, and 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone (5-HPMF), possess anti-inflammation and regulation of immune activity among others. "
4.	Experimental Arthritis 01/13/2021 - "Protective Effect of Tangeretin and 5-Hydroxy-6,7,8,3',4'-Pentamethoxyflavone on Collagen-Induced Arthritis by Inhibiting Autophagy via Activation of the ROS-AKT/mTOR Signaling Pathway."

Related Drugs and Biologics

1.	5-hydroxy-6,7,8,4'-tetramethoxyflavone
2.	5- hydroxy- 3,6,7,8,3',4'- hexamethoxyflavone
3.	tangeretin
4.	Mitogen-Activated Protein Kinases
5.	Proliferating Cell Nuclear Antigen (PCNA)
6.	Flavonoids
7.	chenpi
8.	nobiletin