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P1- 2- (methylthio)adenosyl- P2- 1- (4,5- dimethoxy- 2- nitrophenyl)ethyl pyrophosphate
a caged nucleotide that is a dual P2Y1 and P2Y12 receptor agonist; structure in first source
Also Known As:
MRS 2703; MRS-2703; MRS2703
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleotides: 140
Adenine Nucleotides: 1066
Adenosine Diphosphate: 4554
P1-2-(methylthio)adenosyl-P2-1-(4,5-dimethoxy-2-nitrophenyl)ethyl pyrophosphate: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Ribonucleotides: 307
Adenine Nucleotides: 1066
Adenosine Diphosphate: 4554
P1-2-(methylthio)adenosyl-P2-1-(4,5-dimethoxy-2-nitrophenyl)ethyl pyrophosphate: 1
Purine Nucleotides: 140
Adenine Nucleotides: 1066
Adenosine Diphosphate: 4554
P1-2-(methylthio)adenosyl-P2-1-(4,5-dimethoxy-2-nitrophenyl)ethyl pyrophosphate: 1
Experts
1.
Besada, Pedro
: 1 article (03/2008)
2.
Gachet, Christian
: 1 article (03/2008)
3.
Gao, Zhan-Guo
: 1 article (03/2008)
4.
Hechler, Béatrice
: 1 article (03/2008)
5.
Jacobson, Kenneth A
: 1 article (03/2008)
Related Diseases
1.
Astrocytoma (Pilocytic Astrocytoma)
03/15/2008 - "
Although MRS2703 is itself inactive at human P2Y(1) and P2Y(12) receptors expressed heterologously in 1321N1 astrocytoma cells or in washed human platelets, this derivative readily regenerates the parent agonist upon mild irradiation with long-wave UV light (360 nm).
"