HXR9 peptide

a synthetic antineoplastic small cell-permeable peptide; antagonist of the interaction between HOX proteins and PBX, a second homeodomain-containing transcription factor that modifies HOX activity; this antagonist can block the growth of murine B16 cells and trigger apoptosis both in vitro and in vivo when administered to mice with flank tumors

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Butler-Manuel, Simon: 1 article (10/2016)
2.	Kavitha Madhuri, Thumuluru: 1 article (10/2016)
3.	Kelly, Zoe: 1 article (10/2016)
4.	Kierzek, Andrzej M: 1 article (10/2016)
5.	McGrath, Sophie: 1 article (10/2016)
6.	Michael, Agnieszka: 1 article (10/2016)
7.	Moller-Levet, Carla: 1 article (10/2016)
8.	Morgan, Richard: 1 article (10/2016)
9.	Pandha, Hardev: 1 article (10/2016)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 10/01/2016 - "Targeting the HOX/PBX dimer with the HXR9 peptide enhanced the cytotoxicity of cisplatin in platinum-resistant ovarian cancer. "

Related Drugs and Biologics

1.	Platinum
2.	Cisplatin (Platino)