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leucomelone

an enoyl-ACP reductase (FabK) inhibitor; isolated from Streptococcus pneumoniae; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Catechols: 121
        leucomelone: 1
- Quinones: 434
  - Benzoquinones: 25
    - leucomelone: 1

Experts

1.	Arzanlou, Mahdi: 1 article (04/2019)
2.	Babai-Ahari, Asadollah: 1 article (04/2019)
3.	Helaly, Soleiman E: 1 article (04/2019)
4.	Narmani, Abolfazl: 1 article (04/2019)
5.	Praditya, Dimas F: 1 article (04/2019)
6.	Stadler, Marc: 1 article (04/2019)
7.	Steinmann, Eike: 1 article (04/2019)
8.	Surup, Frank: 1 article (04/2019)
9.	Teponno, Rémy Bertrand: 1 article (04/2019)
10.	Wittstein, Kathrin: 1 article (04/2019)

Related Diseases

1.

Carcinoma (Carcinomatosis)

04/01/2019 - "While only moderate antimicrobial effects were observed, the terphenyl quinone derivatives 3-6 and leucomelone (10) exhibited significant cytotoxicity against the mouse fibroblast L929 and cervix carcinoma KB-3-1 cell lines with IC50 values ranging from 2.4 to 26 μg/mL. Furthermore, metabolites 4-6 showed interesting antiviral activity against hepatitis C virus (HCV)."

Related Drugs and Biologics

1.	Antiviral Agents (Antivirals)
2.	quinone (benzoquinone)