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mono(2-ethyl-5-hydroxyhexyl) phthalate

a metabolite of bis(2-ethylhexyl) phthalate

Also Known As:

MEHHP cpd; mono(2-ethyl-5-hydroxyhexyl)phthalate

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - mono(2-ethyl-5-hydroxyhexyl) phthalate: 9

Experts

1.	Zhang, Yu: 2 articles (01/2021 - 10/2017)
2.	Basirat, Zohreh: 1 article (11/2022)
3.	Ebrahimpour, Karim: 1 article (11/2022)
4.	Golestanzadeh, Mohsen: 1 article (11/2022)
5.	Goodarzi-Khoigani, Masoomeh: 1 article (11/2022)
6.	Kelishadi, Roya: 1 article (11/2022)
7.	Shahrbanoo Daniali, Seyede: 1 article (11/2022)
8.	Yazdi, Maryam: 1 article (11/2022)
9.	Zarean, Elaheh: 1 article (11/2022)
10.	Calafat, Antonia M: 1 article (01/2021)

Related Diseases

1.	Non-alcoholic Fatty Liver Disease 01/01/2021 - "Among the participants (mean age 46 years, 47.5% male), the prevalence of NAFLD was associated with urinary levels of mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono-(2-ethyl-5-oxohexyl) phthalate, mono-(2-ethyl-5-carboxypentyl) phthalate, mono-benzyl phthalate (MBzP), and mono-n-butyl phthalate (MnBP) compared to the reference group. "
2.	Overweight 11/01/2022 - "After extraction of phthalate metabolites, 4 phthalate metabolites including mono-butyl phthalate (MBP; normal: 0.08 ± 0.79; overweight: 0.20 ± 1.11; obese: 0.07 ± 1.07; p-value: 0.405), mono-benzyl phthalate (MBzP; normal: 7.54 ± 6.69; overweight: 7.48 ± 7.16; obese: 8.67 ± 12.75; p-value: 0.729), mono(2-ethyl-5-oxohexyl) phthalate (MEOHP; normal: 4.27 ± 6.36; overweight: 3.03 ± 8.44; obese: 3.53 ± 7.04; p-value: 0.245), and mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP; normal: 246.18 ± 189.80; overweight: 238.48 ± 200.23; obese: 287.65 ± 206.70; p-value: 0.723) were simultaneously detected in samples of maternal amniotic fluid. "
3.	Premature Birth (Birth, Premature) 01/01/2021 - "BKMR models further showed that maternal preconception BPA and mono(2-ethyl-5-hydroxyhexyl) phthalate, and paternal preconception mono(2-ethylhexyl) phthalate were positively associated with preterm birth when the remaining mixture components were held at their median concentrations. "
4.	Polyps 01/15/2023 - "After adjusting for covariates, individual chemical analyses showed that urinary monobenzyl phthalate (MBzP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono(2-ethyl-5-carboxypentyl) phthalate (MECPP), mono(2-ethyl-5-oxohexyl) phthalate (MEOHP), mono(2-ethylhexyl) phthalate (MEHHP) and the sum of di(2-ethylhexyl) phthalate (ΣDEHP) were associated with increased risks of endometrial polyp, with adjusted odds ratios ranging from 2.62 (95% CI: 0.88, 7.84) for MECPP to 6.96 (95% CI: 1.87, 25.87) for ΣDEHP comparing the extreme exposure categories (all P for trends <0.05 or = 0.057). "
5.	Leiomyoma (Uterine Fibroids) 11/22/2022 - "Here, among the most commonly encountered phthalate metabolites, we found the strongest association between the urine levels of mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), the principal DEHP metabolite, and the risk of uterine leiomyoma diagnosis (n = 712 patients). "

Related Drugs and Biologics

1.	phthalic acid (phthalate)
2.	mono(2-ethyl-5-oxohexyl)phthalate
3.	mono-benzyl phthalate
4.	Diethylhexyl Phthalate (DEHP)
5.	Dibutyl Phthalate (Butyl Phthalate)
6.	2-methyl-5,6-cyclopentapyrimidine
7.	mono-(2-ethylhexyl)phthalate
8.	Matrix Metalloproteinases (MMPs)
9.	Organic Chemicals (Chemicals, Organic)
10.	mono-isobutyl phthalate