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2,3,4,10- tetrahydro- 7,10- dimethyl- 2,4- dioxobenzo(g)pteridine

Also Known As:

Ro 08-2750

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Flavins: 50
        2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxobenzo(g)pteridine: 2
  - 3-Ring Heterocyclic Compounds
    - Flavins: 50
      - 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxobenzo(g)pteridine: 2
Enzymes and Coenzymes: 1
- Coenzymes: 558
  - Flavins: 50
    - 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxobenzo(g)pteridine: 2
Biological Factors: 2472
- Biological Pigments: 1
  - Flavins: 50
    - 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxobenzo(g)pteridine: 2

Experts

1.	Artero, Ruben: 1 article (09/2021)
2.	Bargiela, Ariadna: 1 article (09/2021)
3.	Moreno, Nerea: 1 article (09/2021)
4.	Poyatos-Garcia, Javier: 1 article (09/2021)
5.	Sabater-Arcis, Maria: 1 article (09/2021)
6.	Vilchez, Juan J: 1 article (09/2021)
7.	Cai, Shaoxi: 1 article (12/2016)
8.	Chen, Sijia: 1 article (12/2016)
9.	Cheng, Longcong: 1 article (12/2016)
10.	He, Qiyi: 1 article (12/2016)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 12/06/2016 - "The inhibitors of NGF/NGFRs, such as Ro 08-2750, K252a and LM11A-31,can all block NGF-stimulated changes of gene expression or migratory behavior on ovarian cancer cells. "
2.	Atrophy 09/03/2021 - "Using gene-silencing strategies (small interfering RNAs [siRNAs] and gapmers) and the small molecule MSI2-inhibitor Ro 08-2750, we demonstrate that reducing MSI2 levels or activity boosts miR-7 expression, represses excessive autophagy, and downregulates atrophy-related genes of the UPS system. "

Related Drugs and Biologics

1.	Nerve Growth Factor (NGF)
2.	staurosporine aglycone (K252a)