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apicularen B

isolated from Chondromyces; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - apicularen B: 1
  - Polyketides: 231
    - Macrolides: 4391
      - apicularen B: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Polyketides: 231
    - Macrolides: 4391
      - apicularen B: 1

Experts

1.	Hirasawa, Noriyasu: 1 article (02/2007)
2.	Hong, JangJa: 1 article (02/2007)
3.	Ishihara, Kenji: 1 article (02/2007)
4.	Kang, Young-Sook: 1 article (02/2007)
5.	Kwak, Jong Hwan: 1 article (02/2007)
6.	Nakano, Yasuhiro: 1 article (02/2007)
7.	Niikura, Kazuaki: 1 article (02/2007)
8.	Oh, Joa Sub: 1 article (02/2007)
9.	Ohuchi, Kazuo: 1 article (02/2007)
10.	Sasaki, Hirokazu: 1 article (02/2007)

Related Diseases

1.

Bone Resorption

02/01/2007 - "Our findings indicate that apicularen A inhibits bone resorption induced by PTH or IL-1beta more potently than apicularen B, probably due to inhibition of the V-ATPase."
02/01/2007 - "Bone resorption in cultures of mouse calvariae induced by human parathyroid hormone (PTH) or interleukin-1beta (IL-1beta) was inhibited by apicularen A at 10 and 100 nM, while apicularen B had no effect. "

Related Drugs and Biologics

1.	Interleukin-1beta (Interleukin 1 beta)
2.	Parathyroid Hormone (Parathormone)
3.	Dihydrotachysterol (AT 10)
4.	Adenosine Triphosphatases (ATPase)
5.	apicularen A