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gamma-glutamyl-leucine

RN given for (L,L)-isomer

Also Known As:

gamma-Glu-Leu; gamma-glutamyl-leucine, (D,L)-isomer; gamma-glutamylleucine

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - gamma-glutamyl-leucine: 4

Experts

1.	Bazzano, Lydia A: 1 article (01/2022)
2.	Cao, Jie: 1 article (01/2022)
3.	Chen, Ji-Chun: 1 article (01/2022)
4.	Chen, Jing: 1 article (01/2022)
5.	Gu, Dongfeng: 1 article (01/2022)
6.	He, Hua: 1 article (01/2022)
7.	He, Jiang: 1 article (01/2022)
8.	He, William J: 1 article (01/2022)
9.	Kelly, Tanika N: 1 article (01/2022)
10.	Li, Changwei: 1 article (01/2022)

Related Diseases

1.	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/01/2022 - "Gamma-glutamyl-leucine (Gamma-Glu-Leu) has been extensively reported to be associated with the risk of cardio-metabolic diseases, such as obesity, metabolic syndrome, and type 2 diabetes. "
2.	Prostatic Neoplasms (Prostate Cancer) 10/25/2022 - "Notably, higher levels of the phospholipid choline, amino acid glutamate, long-chain polyunsaturated fatty acid (n6) arachidonate (20:4n6), and glutamyl amino acids gamma-glutamylglutamate, gamma-glutamylglycine, and gamma-glutamylleucine were associated with increased risk of prostate cancer-specific mortality (fourth versus first quartile HRs=2.07-2.14; P-values <5.2×10-5). "
3.	Ovarian Neoplasms (Ovarian Cancer) 07/01/2022 - "7-alpha-hydroxy-3-oxo-4-cholestenoate (ORIVW =1.45; 95% CI: 1.06-1.97; PIVW =0.018), gamma-glutamylisoleucine (ORIVW =1.40; 95% CI: 1.16-1.69; PIVW =0.0004), 1-oleoylglycerophosphocholine (ORIVW =1.22; 95% CI: 1.1-1.35; PIVW =0.0001), gamma-glutamylleucine (ORIVW =4.74; 95% CI: 1.18-18.93; PIVW =0.027) were the most dangerous metabolites for lung cancer, ovarian cancer, breast cancer, and glioma, respectively; while pseudouridine (ORIVW =0.50; 95% CI: 0.30-0.83; PIVW =0.007), 2-methylbutyroylcarnitine (ORIVW =0.77; 95% CI: 0.68-0.86; PIVW =2.9×10-6), 2-methylbutyroylcarnitine (ORIVW =0.77; 95% CI: 0.70-0.85; PIVW =3.4×10-7), glycylvaline (ORIVW =0.13; 95% CI: 0.02-0.75; PIVW =0.021) were associated with lower risk of lung cancer, ovarian cancer, breast cancer, and glioma, respectively. "
4.	Obesity 01/01/2022 - "Gamma-glutamyl-leucine (Gamma-Glu-Leu) has been extensively reported to be associated with the risk of cardio-metabolic diseases, such as obesity, metabolic syndrome, and type 2 diabetes. "
5.	Metabolic Diseases (Metabolic Disease) 01/01/2022 - "Gamma-glutamyl-leucine (Gamma-Glu-Leu) has been extensively reported to be associated with the risk of cardio-metabolic diseases, such as obesity, metabolic syndrome, and type 2 diabetes. "

Related Drugs and Biologics

1.	Glutamic Acid (Glutamate)
2.	gamma-glutamyl-leucine
3.	Sulfates (Sulfates, Inorganic)
4.	Pseudouridine
5.	Phospholipids (Phosphatides)
6.	Ketoglutaric Acids (Ketoglutaric Acid)
7.	Glucose (Dextrose)
8.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)
9.	Choline (Choline Chloride)
10.	Amino Acids