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glibornuride
was MH 1975-92 (see under SULFONYLUREA COMPOUNDS 1975-90); use SULFONYLUREA COMPOUNDS to search GLIBORNURIDE 1975-92; an oral, sulfonylurea hypoglycemic agent which stimulates insulin secretion
Also Known As:
Gluborid; Glutril; Ro 6-4563; Ro-6-4563
Networked:
18
relevant articles (
0
outcomes,
2
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Urea: 15015
Sulfonylurea Compounds: 35
glibornuride: 18
Sulfur Compounds: 278
Sulfones: 534
Sulfonylurea Compounds: 35
glibornuride: 18
Experts
1.
Orak, Haci
: 1 article (03/2006)
2.
Ozgey, Yasemin
: 1 article (03/2006)
3.
Ozsoy-Sacan, Ozlem
: 1 article (03/2006)
4.
Tunali, Tugba
: 1 article (03/2006)
5.
Yanardag, Refiye
: 1 article (03/2006)
6.
Yarat, Aysen
: 1 article (03/2006)
Related Diseases
1.
Type 2 Diabetes Mellitus (MODY)
01/01/1975 - "
The multiple-dose pharmacokinetics of 1-(2-endo-hydroxy-3-endo-bornyl)-3-(p-tolyl-sulfonyl)-urea (glibornuride, Glutril¿) was examined in 7 subjects with maturity-onset diabetes treated with the drug over a period of 4 weeks (25 mg every twelve hours).
"
05/01/1974 - "
A clinical trial of glibornuride in maturity-onset diabetes mellitus.
"
03/01/1998 - "
The effect of glibornuride on the plasma ANF levels and natriuresis was estimated in 10 newly diagnosed NIDDM patients and 10 control subjects.
"
03/01/1998 - "
The Effect of Glibornuride on Plasma Atrial Natriuretic Factor Levels in Patients with Newly Diagnosed NIDDM.
"
09/01/1976 - "
Clinical comparison between glibornuride (Glutril) and tolbutamide in maturity-onset diabetes: a controlled double-blind trial.
"
2.
Diabetes Mellitus
04/01/1973 - "
Long term treatment of diabetes mellitus with glibornuride.
"
11/10/1972 - "
[Comparative study with tolbutamide and glibornuride for the diagnosis of latent diabetes mellitus].
"
09/01/1975 - "
The authors present the results of treatment of the patients with diabetes mellitus with hypoglycaemic preparations (sulphonylurea preparations of the second generation): glibenclamide, glibornuride and glydiazinamide.
"
3.
Hypoglycemia (Reactive Hypoglycemia)
01/01/1992 - "
All 98 cases of sulfonylurea-induced hypoglycemia reported by the 30 regional drug-monitoring centers between 1985 and 1990 were analyzed: 46 with gliclazide, 40 with glibenclamide, 5 with glipizide, 1 with glibornuride and 6 with first-generation sulfonylureas.
"
02/01/1986 - "
The risk of hypoglycemia occurring is thus significantly higher under glibenclamide and chlorpropamide than under glibornuride and tolbutamide.
"
4.
Flushing
06/01/1994 - "
Evident flushing phenomenon was observed in 6 patients treated with chlorpropamide, in 3 treated with tolbutamide, in 2 treated with glibenclamide, in one receiving glibornuride and in none treated with glipizide.
"
06/01/1993 - "
Evident flushing phenomenon was observed in 6 patients treated with chlorpropamide, in 3 treated with tolbutamide, in 2 treated with glibenclamide, in one receiving glibornuride and in none treated with glipizide.
"
5.
Urticaria (Hives)
03/01/1991 - "
With special regard to cross reactions between sulfonylurea: we observe the tolerance of glipizide after glibenclamide induced urticaria, tolerance of glicalazide after glibornuride induced Quincke's oedema and eruption, tolerance of glibornuride after chlorporpamide induced urticaria and Quincke's oedema.
"
03/01/1991 - "
We describe 5 observations of cutaneous reactions or immediate hypersensitivity with different hypoglycemic sulfonylurea: Quincke's oedema with glibornuride, three urticaria (one was followed by bronchospasm and collapsus) with glibenclamide, one bullous dermatitis with carbutamide.
"
Related Drugs and Biologics
1.
glibornuride
2.
Glyburide (Glibenclamide)
3.
Tolbutamide (Orinase)
4.
Glipizide (Glucotrol)
5.
Insulin (Novolin)
6.
Chlorpropamide
7.
Solutions
8.
Blood Glucose (Blood Sugar)
9.
N-Acetylneuraminic Acid (Sialic Acid)
10.
Uric Acid (Urate)