ICI 170777

has positive ionotropic & vasodilator effets; structure given in first source

Also Known As:

6-methyl-5-(pyridy-4-yl)-3H,6H-1,3,4-thiadiazin-2-one; ICI-170777

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

1.	Heart Failure 06/01/1989 - "6. The positive inotropic action and balanced arterial and venous dilator effect of ICI 170777 indicate that the compound may be useful in the treatment of congestive heart failure, a disorder that is characterized by decreased cardiac contractility and enhanced arterial and venous constrictor tone."
2.	Ganglion Cysts (Ganglion) 06/01/1989 - "In the ganglion-blocked anaesthetized dog, infusion of a low dose of ICI 170777 which had no effect on the basal left ventricular dP/dtmax, selectively potentiated the positive inotropic effects of isoprenaline. "

1.	Isoproterenol (Isoprenaline)