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2,6-diaminopurine 2',3'-didehydro-2',3'-dideoxyriboside
HIV virus replication inhibitor; structure given in first source
Also Known As:
ddeDAPR
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Deoxyribonucleosides: 34
Dideoxynucleosides: 27
2,6-diaminopurine 2',3'-didehydro-2',3'-dideoxyriboside: 1
Related Diseases
1.
Acquired Immunodeficiency Syndrome (AIDS)
05/29/1987 - "
In contrast to ddAdo, which is rapidly deaminated by beef intestine adenosine deaminase at an initial velocity (Vi) of 145 mumol/mg protein/min, ddDAPR and ddeDAPR are poor substrates for the enzyme (Vi: 8 and 0.7 mumol/mg protein/min, respectively), which further contributes to the potential of ddDAPR as a chemotherapeutic agent against AIDS.
"
Related Drugs and Biologics
1.
Proteins (Proteins, Gene)
2.
Enzymes
3.
Adenosine Deaminase
4.
2,6-diaminopurine 2',3'-dideoxyriboside