beta-granins
MW 21 kDa co-secreted peptides of insulin granule closely related to chromogranin A
Also Known As:
beta-granin; betagranin
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Bio-Agent Context: Research Results
Related Diseases
1. | Insulinoma
03/01/1988
- " Antibodies raised to insulinoma betagranin recognized antigens of the same molecular size (approximately 20,000 daltons) in insulinoma tissue and normal islets. " 03/01/1988
- " The tissue and subcellular distribution of betagranin, a chromogranin A-related, cosecreted protein produced in rat insulinoma tissue, has been investigated using a combination of density gradient centrifugation, immunoblotting, immunofluorescence, and immunoelectron microscopic techniques. " 06/01/1987
- " The nature and subcellular localization of the enzymic activities responsible for the production of the 20 kDa protein betagranin from its 100 kDa chromogranin-A-like precursor was investigated in transplantable insulinoma tissue. " 06/01/1987
- " The biosynthesis of insulin and betagranin, a 20-21 kDa co-secreted chromogranin A-related protein, were investigated in isolated insulinoma cells and islets. " 08/29/1988
- " The cDNA encoding the precursor form of the chromogranin A-related proteins, beta-granin and pancreastatin, was obtained by immune screening of rat insulinoma and pancreatic islet cDNA libraries. "
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