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D 15414

hydroxy derivative of D 16726; structure given in first source

Also Known As:

1H-Indol-5-ol, 1-ethyl-2-(4-hydroxyphenyl)-3-methyl-; D-15414

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - D 15414: 1

Related Diseases

1.

Breast Neoplasms (Breast Cancer)

04/01/1985 - "The growth of estrogen receptor-positive MCF-7 breast cancer cells was inhibited by the hydroxy derivative D 15414 (10(-8)-10(-5) M). "
04/01/1985 - "Because of the high binding affinity of D 15414 for the estrogen receptor (RBA 6.7-10.0) and the lack of activity against hormone-independent MDA-MB 231 breast cancer cells, a specific mode of action involving the estrogen receptor is likely."

Related Drugs and Biologics

1.	Estrogen Receptors
2.	Hormones (Hormone)